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URANS modeling of three airfoils with different stall mechanisms
Published 2017“…However, transition effect is not accounted for and hence, all test cases are run fully turbulent. Significant differences in the flow predictions of all models are noticed in regions with massively flow separation.…”
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Characterization and Modeling of Damage in Steel at Different Strain Rates
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An operator-splitting approach with a hybrid finite volume/finite difference scheme for extended Boussinesq models
Published 2024“…In this paper, we present a hybrid numerical scheme combining finite volume and finite difference methods (FV/FD), for solving two extended Boussinesq-type (BT) models. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Conclusions</h3><p dir="ltr">We show that our network differencing procedure can effectively and efficiently detect statistical significant network re-wirings in different conditions. …”
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
Published 2011“…Several authors/ researchers have made an attempt to touch upon the different dimensions associated with PD programs. This dissertation attempts to study the significance of staff professional development for educators and how it can affect students’ achievement. …”
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Effect of corporate ethics and social responsibility on OCB: the role of employee identification and perceived CSR significance
Published 2021“…Partial least square structural equation modeling (PLS-SEM) is used to analyze the data and multi-group analysis is conducted to investigate the role of perceived CSR significance. …”
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Machine Learning Based Photovoltaics (PV) Power Prediction Using Different Environmental Parameters of Qatar
Published 2019“…The ANN model outperforms other regression models, such as a linear regression model, M5P decision tree and gaussian process regression (GPR) model. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”