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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression
Published 2016“…Tumorsphere formation is one of the indicators of aggressiveness in malignant cancers, which was significantly inhibited in IMR-32 cells after L1-CAM KD or Sutent treatment, however, no synergistic effect was observed with dual treatments, rather L1-CAM KD alone showed a greater inhibition on tumorsphere formation compared to Sutent treatment alone. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Total hip arthroplasty: Evolution of the use of dual mobility cups in Lebanon
Published 2018“…Recurrent dislocation, being a major reason for revision total hip arthroplasty (THA), was found to decrease significantly using dual mobility cup (DMC) compared to standard cups (SC), and that in both primary and revision THA. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Dual-stage segmentation and classification framework for skin lesion analysis using deep neural network
Published 2025“…This study aims to develop a dual-stage deep learning framework for the segmentation and classification of skin lesions, addressing challenges such as imbalanced data, lesion variability, and low contrast.…”
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The Effects of Subtitles on Second Language Vocabulary Learning
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A dual-stage deep learning approach for robust detection and identification of hardware trojans using monte-carlo dropout
Published 2025“…This paper presents a dual-path deep learning framework for the detection and identification of HTs via side-channel analysis. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Predicting Mobile Game Success Using Data Analytics
Published 2017“…This study addresses these challenges through data driven research of the mobile gaming application market, mobile gaming application features, user acquisition and retention trends, and monetization strategies using the CRISP-DM model for data mining in order to prove a successful method for predictions of mobile game application success. …”
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Comparison of Single‐Coil Versus Dual‐Coil Implantable Cardioverter Defibrillator Devices: A Systematic Review and Meta‐Analysis of Efficacy and Extraction‐Related Outcomes
Published 2025“…In addition, all‐cause mortality was significantly elevated in the dual‐coil cohort (HR: 0.91; 95% CI: 0.87–0.97; <i>p</i> = 0.001). …”
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Efficacy of Tirzepatide Dual GIP/GLP‐1 Receptor Agonist in Patients With Idiopathic Intracranial Hypertension. A Real‐World Propensity Score‐Matched Study
Published 2025“…While GLP‐1 receptor agonists have shown promise in IIH management, the potential of dual GIP/GLP‐1 receptor activation through tirzepatide remains unexplored. …”
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Exploring the potential of onboard energy scavenging subsystems for generating valuable data
Published 2023“…<p dir="ltr">We propose implementing an onboard energy scavenging subsystem utilizing piezoelectric materials, which serves the dual purpose of generating electrical energy and facilitating data acquisition for multifaceted applications. …”
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Toward Adaptive Intrusion Detection Systems for UAVs Using Cyber-Physical Image Analysis
Published 2025“…The framework transforms tabular sensor data into multichannel image representations using a novel Gramian Angular Field (GAF) method that we developed and named Dual-GAF, enabling high-fidelity feature extraction and contextual data consideration via Convolutional Neural Networks (CNNs). …”