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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
Published 2021“…This rapid growth coincided with two phenomena worthy of attention, the first being the conjunction of this growth with the significant decline in residential density, and the second with the phenomenon of the increase in the proportion of non-durable residential lands, which reached 49% (DTPS, 1998) of the total land allocated to citizens. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Editorial: Special Issue - Economics in Digital Construction
Published 2024“…These advancements promise substantial economic benefits, ranging from increased productivity to enhanced decision-making capabilities, which, in turn, can spur significant growth in the broader economy. …”
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Economic policy uncertainty: Global energy security with diversification
Published 2024“…This study also demonstrates that labor capital shifts have a significant effect on ED. The quantitative results reveal the importance of clear and precise economic policies for increasing investment in carbon-free energy security.…”
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Techno-Economic Analysis of Autotrophic Microalgae for Biofuel Production in India
Published 2013“…Modern society relies on non-renewable sources of energy which is the dominant source of energy, which accounts for nearly 84% of the overall increase in demand between 2005 and 2030 (Khan et al., 2009). …”
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Estimating Economic and Environmental Benefits of Urban Trees in Desert Regions
Published 2020“…<p>Trees in urban areas have a significant impact on air quality and other environmental issues. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Revisiting the economic theory of crime A state-level analysis in India
Published 2023“…<p dir="ltr">The economic theory of crime tends to suggest that deterrence variables have a significant impact on crime rates in a society. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Evaluating the economic impact of clinical pharmacist interventions in the women’s health setting in Qatar
Published 2025“…The sensitivity analysis confirmed that the outcomes are robust, demonstrating a 100% probability for positive economic benefits in all simulated cases.</p><h3>Conclusion</h3><p dir="ltr">Although there was an observed increase in resource utilization resulting from clinical pharmacists’ interventions, this study highlights their crucial role in mitigating the costs associated with preventable adverse drug events.…”
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Thermo-economic Optimization of Hybrid Combined Power Cycles Using Heliostat Field Collector
Published 2016Get full text
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A Stackelberg Game Inspired Model of Real-Time Economic Dispatch with Demand Response
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The Impact of Capital Formation on Economic Diversification in GCC Countries—Empirical Analysis Based on the PVAR Model
Published 2023“…<p dir="ltr">Economic diversification has been a cornerstone of the policy agenda of resource-rich countries, such as Gulf Cooperation Council (GCC) countries, seeking sustainable economic development to avoid reliance on hydrocarbon revenues that cause significant vulnerabilities and economic, social, and political instability in the long term. …”