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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Effect of technology integration in teaching quadratic functions .... (c2011)
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The effect of teaching strategies on learning a foreign language. (c2004)
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Effects of Dunn and Dunn learning styles model on achievement and motivation. (c2013)
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Conclusions</h3><p dir="ltr">We show that our network differencing procedure can effectively and efficiently detect statistical significant network re-wirings in different conditions. …”
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The effect of CEO ownership & CEO entrenchment on firm value. (c2011)
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Effectiveness of 2D magnesium phosphate hydrogel for surgical decontamination of dental implants: A case series
Published 2024“…Radiographic evaluations were conducted to assess the exposure of implant threads. The findings revealed a statistically significant decrease in probing depth, bleeding on probing, and the number of exposed implant threads following treatment with the magnesium phosphate hydrogel, though the exact role of the hydrogel in these improvements warrants further exploration.…”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…A higher proportion of vitiligo was also noted: 14% in the total patient population reported, and 18% in insulin-treated patients.…”
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An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat...
Published 2022“…Consequently, choosing a system to enhance water infiltration in an agricultural terrain seems site-specific. …”
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The worthiness and effectiveness of mathematics remedial courses: a case study
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