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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The nexus between debt structure, firm performance, and the financial crisis: non-linear panel data evidence from Japan
Published 2022“…This is the first study that looks at the effect of the short-term debt threshold on corporate performance, as well as the influence of the 2008 global financial crisis (GFC) on the nonlinear effect of debt structure on corporate performance. …”
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Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injury
Published 2021“…Band area and intensity ratios, band frequency and bandwidth values of specific spectral bands showed that TBI causes significant structural and contextual global changes including decrease in carbonyl content, unsaturated lipid content, lipid acyl chain length, membrane lipid order, total protein content, lipid/protein ratio, besides increase in membrane fluidity with an altered protein secondary structure and metabolic activity in hippocampus 24 h after injury. …”
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Carbon Nanotube Effect on the Ductility, Flexural Strength, and Permeability of Concrete
Published 2019“…In this research, the effect of CNT use on the flexural strength, strain capacity, permeability, and microstructure of concrete was investigated. …”
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Modulation of gut microbiota: The effects of a fruits and vegetables supplement
Published 2022“…This study aimed to demonstrate the effectiveness of a formulated fruit and vegetable supplement (FVS) in modulating the antioxidant capacity and the gut microbiota composition. …”
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Semaglutide also slowed weight regain and promoted weight loss after failed bariatric surgery. It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …”
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
Published 2025“…Semaglutide also slowed weight regain and promoted weight loss after failed <u>bariatric surgery.</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …”
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The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere
Published 2024“…Here, we studied the effect of plant genotype and type of fertilizers on the eukaryotic community structures of the date palm rhizosphere. …”
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Effects of ethanol addition to diesel–biodiesel blends on the CI engine characteristics
Published 2024“…<p dir="ltr">This research work investigates the effects of adding ethanol to biodiesel–diesel blends on the performance and emissions of a single-cylinder, four-stroke, air-cooled compression-ignition engine. …”
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…In this study, we investigated the effects of tumor LDHC expression on immune responses.…”
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Nonlinear effects in locally resonant nanostrip phononic metasurface at GHz frequencies
Published 2021“…<p dir="ltr">In this paper, we report on the observation of nonlinear effects in a nanostrip phononic metasurface (NPM) that enable the tuning of resonance frequencies at 1.42 GHz. …”
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Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity
Published 2024“…In the ramp test, there was a significant decrease in muscle activation for rmsRF% (<i>P</i>= 0.049; d = 0.61) and rmsVM% (<i>P</i> = 0.01; d = 0.84) in peak power output (PPO). …”
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Adaptive Effects of Seeing Green Environment on Psychophysiological Parameters When Walking or Running
Published 2019“…This corroborates the calming and relaxing effect of green on the human organism. Study 2 showed that running in a green environment was associated with an increased level of perceived exertion at similar speeds (compared to other color conditions), while exposure to red induced a significant decrease in the level of tension. …”