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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…Our results show that no significant association with age was observed. However, the previously reported increase of LINE-1 methylation in males was reconfirmed. …”
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Smart binary phase‐coding for pulse‐compression radar: An electronic protection technique against repeater jamming
Published 2024“…If the radar does not change its parameters from pulse to pulse, such smart jamming techniques applied in this way can be very effective. In this article, the authors propose to use a smart binary phase‐coding method for pulse compression radar as an electronic protection technique against repeater jamming. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…Most studies show equal efficacy of both drugs but with a better side effect profile with ibuprofen treatment. While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. …”
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Experimental investigation and multi-scale Mori–Tanaka modeling of viscoelastic asphalt mastic with imperfect interfaces
Published 2025“…While the proposed model effectively captures the physical interactions in asphalt mastics, it requires further refinement to account for the additional influence of chemical reactions between fillers, such as hydrated lime, and the asphalt binder.…”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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The effect of 595 nm pulsed dye laser on superficial and nodular basal cell carcinomas
Published 2009“…The objective of this study was to determine the effect of repeated PDL treatments on BCCs of superficial and nodular subtypes and of varying diameters. …”
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The Effect of Oral Feedback in Secondary Classrooms on Arab Female Students’ Acquisition of English Past Tense
Published 2013“…The present study investigated the effect of oral feedback on Arab female students’ uptake and acquisition of English regular and irregular past tense in the context of secondary EFL classrooms in the UAE. …”
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The effect of a sand surface on physical performance responses of junior male handball players to plyometric training
Published 2020“…<h2>Background</h2><p dir="ltr">The effects of 7 weeks plyometric training on a stable surface and on sand were compared in junior male handball players.…”
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Effects of recording food intake using cell phone camera pictures on energy intake and food choice
Published 2015“…The effectiveness and acceptability of cell phone picture–based diet recording also was assessed. …”
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