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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment
Published 2020“…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Consortium Blockchain-Based Decentralized Stock Exchange Platform
Published 2020“…Each organization manages its system and collaborates with the others to facilitate trading on the stock exchange platform, and typically buy-sell orders go through different parties before settlement. …”
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…<p dir="ltr">Maintaining a stable exchange rate is a challenging task for the world, especially for developing economies. …”
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Exchange Rate Volatility and ESG Performance: An International Empirical Analysis
Published 2024“…By employing a comprehensive set of statistical tests, including the system generalized method of moments (GMM) estimation technique, the research provides robust empirical evidence on how ERV influences different dimensions of ESG performance. The results reveal a significant negative effect of ERV on ESG performance, indicating that greater exchange rate instability adversely impacts firms' sustainability practices across ESG aspects. …”
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Second-law-based performance evaluation of cooling towers and evaporative heat exchangers
Published 2020“…The concept of total exergy as the sum of thermomechanical and chemical parts is employed in calculating the flow exergies for air and water vapor mixtures. For the different input variables investigated, efficiencies were, almost always, seen to increase or decrease monotonically. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Impact of Environmental, Social and Governance Factors on Financial Performance in Indian Firms
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Impact of Ionic Strength and Charge Density on Donnan Potential in the NaCl-Cation Exchange Membrane System
Published 2023“…This work aims to theoretically investigate the effect of both the fixed charge density of ion exchange membranes and the ionic strength of the treated aqueous NaCl solution on the generated Donnan potential at thermodynamic equilibrium conditions. …”
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