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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Power factor correction capacitors; essentials and cautions
Published 2000“…In electrical installations with a low power factor, significant cost savings can be made through the application of power factor correction. …”
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Human factors frameworks in analysis of contributory factors to medication error: A systematic review
Published 2025“…ConclusionHF frameworks are a valuable tool for analysing contributory factors to medication errors. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Teacher's Perspectives and Professional Development Needs to Integrate AI Tools in K-12 Sector in the UAE
Published 2023“…Analysis of the data revealed PU as the most significant factor predicting BI and TPACK and SE significantly predicted PU. …”
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The Contribution of the UAE School Inspection Framework as a Quality Assurance Tool for School Transformation and Performance Improvement
Published 2017“…Among the school global transformation indicators, sustainability is the only factor that supports school performance development. …”
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Utilizing Venue Closed-Circuit Television (CCTV) Surveillance as an Emergency Management Tool to Safeguard Vulnerable Persons
Published 2024“…Stampedes or riots at sporting events are significant concerns to events’ management teams. VP’s are at higher risk of injury in crowded conditions than any other spectators.…”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Application of Tools of Quality Function Deployment and Modified Balanced Scorecard for Optimal Allocation of Pavement Management Resources
Published 2020“…Consequently, the outcome of QFD-BSC analysis is studied in the Fishbone Diagram and Cause-Effect Analysis to graphically present how significant factors in four perspectives will lead to better financial goals in the pavement management industry. …”
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An Exploration of Critical Success Factors of Virtual Distributed Projects
Published 2016“…Further, the research work is further done by exploring the critical success factors which contribute in the accomplishment of projects. …”
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Driving simulation sickness and the sense of presence: Correlation and contributing factors
Published 2021“…Results showed that females reported significantly higher SS scores than males. An increasing trend in the SS was observed with the increase of age. …”