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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Antibiotic resistance patterns and sequencing of class I integron from uropathogenic Escherichia coli in Lebanon
Published 2010“…Significance and Impact of the Study: These findings will facilitate greater understanding of the factors that contribute to the presence and transfer of integron-associated antibiotic resistance genes in UPEC.…”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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An investigations into the factors that associated with writing anxiety for english language learners in UAE universities
Published 2013“…The results also demonstrate that computer use in writing classes and tests was perceived as an anxiety provoking factor and had no significant effects in reducing the participants’ writing anxiety. …”
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Factors associated with functional disability among Lebanese elderly living in rural areas
Published 2018“…The objective is to describe disability risk factors in Lebanese elderly living in rural settings, focusing on the role of polypharmacy, alcohol consumption, and nutrition. …”
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Incidence and Risk Factors Related to Symptomatic Venous Thromboembolic Events After Esophagectomy for Cancer
Published 2016“…Multivariable analysis showed that high American Society of Anesthesiologists (ASA) class (p = 0.008), pneumopathy (p = 0.002), or an acute respiratory distress syndrome (ARDS) (p = 0.015) were significantly associated with VTE. …”
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An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School
Published 2022“…This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. …”
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Cryptosporidium spp., prevalence, molecular characterisation and socio-demographic risk factors among immigrants in Qatar
Published 2019“…The prevalence of Cryptosporidium spp. did not differ significantly between the sexes or age classes but varied significantly between subjects affiliated to different religions with the lowest prevalence among the Muslims. …”
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A Comparative Analysis of Proficiency Scores of University Students in the United Arab Emirates: The Effectiveness of Using a First Language When Teaching a Second Language in a Re...
Published 2013“…This study, an investigation into the effectiveness of using a learner’s first language (L1) to teach a second language (L2) in reading comprehension classes, focuses on tertiary students in the United Arab Emirates (UAE). …”
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Risk Factors of Difficult Intubation in Patients with Severe Obesity Undergoing Bariatric Surgery: A Retrospective Cohort Study
Published 2025“…<h3>Background</h3><p dir="ltr">Obesity poses significant challenges by altering upper airway anatomy and making mask ventilation and tracheal intubation difficult. …”