Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”

Large-scale association analysis identifies new risk loci for coronary artery disease by Deloukas, Panos

“…Coronary artery disease (CAD) is the commonest cause of death. Here, we report an association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching genome-wide significance, taking the number of susceptibility loci for CAD to 46, and a further 104 independent variants (r2 < 0.2) strongly associated with CAD at a 5% false discovery rate (FDR). …”
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”

Can AI Help in Screening Viral and COVID-19 Pneumonia? by Muhammad E. H. Chowdhury (14150526)

“…<p>Coronavirus disease (COVID-19) is a pandemic disease, which has already caused thousands of causalities and infected several millions of people worldwide. …”

STARD 13 in prostate cancer. (c2018) by Saab, Sahar S.

“…Proliferation and migration are known to be regulated by Rho family of GTPases. StarD13 is a GAP for Rho GTPases and has been previously described to be a tumor suppressor in astrocytoma, breast and colorectal cancer. …”
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Exploring the Role of Perceived Organizational Injustice and Organizational Identification in the Impact of Discretionary HR Practices on Counterproductive Behaviors: Evidence from... by El Dimassi, Yasmeen

“…It investigates how customized, flexible HR practices are resource-enhancing tools that decrease workplace deviant behaviors. The study uses survey responses from 214 Lebanese employees working in different sectors to fill a significant knowledge gap in HR studies, primarily focusing on Western business settings. …”
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The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function by MUBARAK, ALIA MARJAN

“…This study addresses a literature gap that exists for such research of global solutions for the local environment. …”
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Vitamin D₃ metabolite ratio as an indicator of vitamin D status and its association with diabetes complications by Lina H. M. Ahmed (9571561)

“…VMR-₃ associated with hypertension (p < 0.05), dyslipidemia (p < 0.001) and coronary artery disease (p < 0.05).</p><h3>Conclusions</h3><p dir="ltr">In this cross sectional study, whilst not causal, VMR-₂ was shown to be the superior predictor of diabetic and cardiovascular complications though not demonstrative of causality in this cross-sectional study population over VMR-₁, VMR-₃ and the individual vitamin D concentration measurements; VMR-₂ associated with both microvascular and cardiovascular indices and therefore may have utility in predicting the development of diabetic complications.…”

Role of family in supporting children with mental disorders in Qatar by Abdulnaser A. Fakhrou (16855155)

“…<h3>Background</h3><p dir="ltr">Mental disorders can significantly impact children's lives and affect their emotional, cognitive, and behavioral development. …”

Severe cardiopulmonary complications of ketamine: Acute pulmonary Edema in a cardiac patient by Tahir Shahzad (21842195)

“…In this case, a middle-aged male with a known history of coronary artery disease and congestive heart failure deteriorated significantly after ketamine was administered for sedation to facilitate a computed tomography pulmonary angiogram. …”

Integrated epigenome, whole genome sequence and metabolome analyses identify novel multi-omics pathways in type 2 diabetes: a Middle Eastern study by Noha A. Yousri (1392577)

“…Fourteen of the loci overlapped published GWAS loci for diabetes related traits and were used to identify causal associations of HK1 and PFKFB2 with HbA1c. …”

Type II diabetes mellitus and hyperhomocysteinemia by Platt, Daniel E.

“…Background Elevated homocysteine (Hc) levels have a well-established and clear causal relationship to epithelial damage leading to coronary artery disease. …”
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The effects of Social Determinants of Health on Type 2 Diabetes Outcomes (A1C) by Awad, Nathalie

“…Background: Diabetes Mellitus is one of the most prevalent chronic diseases in Lebanon and understanding its underlying risk factors beyond the scope of diet and lifestyle is imperative for proper diabetes management. …”
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Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction by Daniel E. Platt (13982757)

“…<h3>Background</h3><p dir="ltr">Elevated homocysteine (Hc) levels have a well-established and clear causal relationship to epithelial damage leading to coronary artery disease. …”

Behavior of axially loaded drilled shaft foundations with symmetric voids outside and inside the caging by Abishdid, Caesar

“…During the construction process, different types of anomalies such as necking, soft-bottom gap at the base, voids and soil intrusions can occur. …”
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Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach by AL BESHER, HUDA ISMAIL

“…The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …”
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Crystallization properties of arsenic doped GST alloys by Vinod E. Madhavan (8136774)

“…The decreases in E_opt for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …”

Frugal innovation for sustainable rural development by Mokter, Hossain

“…This study, therefore, aims to address this gap by examining how frugal innovation can contribute to sustainable development in rural areas. …”
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Impact of global macroeconomic factors on spillovers among Australian sector markets: fresh findings from a wavelet-based analysis by Jiang, Zhuhua

“…Additionally, global macroeconomic factors drive the connectedness of the Australian sectoral indices, with oil and exchange rates moving in phase, and oil volatility, stock volatility and the Infectious Disease Tracker Index moving in antiphase. Global stock and oil market volatility has a significant impact on the Australian sector's returns over short-, medium- and long-term horizons. …”
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Antecedents and consequences on employee turnover intention in the hospitality industry in Lebanon by Baajour, Maya

“…H1 (There is an indirect relationship between PAT and Turnover) showed a significant result that when training is available employees’ intention to leave decreases. …”
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