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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”
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Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…This is in addition to the other effect represented by reducing the direct solar access to the building surfaces and decreases the solar energy gained by the buildings envelop through direct radiation. …”
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3
STARD 13 in prostate cancer. (c2018)
Published 2018“…Our data showed that StarD13 knockdown had no significant effect on prostate cancer cell invasion; further investigations are to be accomplished in order to discover the reasons behind this insignificance.…”
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Antecedents and consequences on employee turnover intention in the hospitality industry in Lebanon
Published 2020“…H1 (There is an indirect relationship between PAT and Turnover) showed a significant result that when training is available employees’ intention to leave decreases. …”
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The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
Published 2018“…The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. However, not all of these projects are completed on time and adhering to the predetermined budget. …”
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Role of family in supporting children with mental disorders in Qatar
Published 2023“…Age has no statistically significant effect on the role of family members in supporting people with mental disorders.…”
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Crystallization properties of arsenic doped GST alloys
Published 2019“…The decreases in E<sub>opt</sub> for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …”
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Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach
Published 2021“…The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …”
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Published 2021“…In this analysis, we address this gap and provide novel estimates of the HIV mortality rate and the number of HIV deaths by age group, sex, and municipality in Brazil, Colombia, Costa Rica, Ecuador, Guatemala, and Mexico.…”
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Behavior of axially loaded drilled shaft foundations with symmetric voids outside and inside the caging
Published 2014“…During the construction process, different types of anomalies such as necking, soft-bottom gap at the base, voids and soil intrusions can occur. …”
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Efficient multi-objective neural architecture search framework via policy gradient algorithm
Published 2024“…Notably, compared with other multi-objective NAS methods, our NAS framework effectively decreases the computational burden (accounting for just 1/6 of the NSGA-Net). …”
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…In addition, a significantly higher CVT (up to 73%) was recorded for eccentric pipes as compared to the concentric cases, primarily due to the reduced fluid velocity in the narrow gap of the eccentric annulus. …”
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub...
Published 2018“…Therefore, the key challenge is to reduce the consumption of fossil fuels which decreases the production of greenhouse gases such as CO2 and CH4 by using renewable energy technologies to provide clean carbon free energy that can combat future energy security challenges. …”
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
Published 2025“…This research addresses critical knowledge gaps regarding living microalgae-mediated mercury removal and demonstrates <i>MIMA's</i> potential as a sustainable, efficient solution for mercury contamination in aquatic ecosystems, maintaining viability even under nutrient-limited conditions while effectively reducing mercury concentrations to near guideline values at the lowest initial level (10 μg/L).…”