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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Oral contraceptive pills and possible adverse effects
Published 2014“…Since their introduction to the market, there have been significant changes in the drug content and formulations of these products, in part to decrease the risk of adverse effects. …”
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Gender differences at work
Published 2015“…The existence of gender inequality at the workplace is a pervasive problem in many countries around the world. …”
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Theorizing Gender in Druze
Published 2023“…This paper highlights factors that influence these roles and identities, specifically in marriage and religious discriminatory laws like divorce. Based on a feminist standpoint and intersectionality theory, this research adopts a social psychological approach to highlight the significance of how the Druze social and political identity shape the Druze marriage institution.…”
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Gender-based violence during COVID-19 lockdown: case study of a community in Lagos, Nigeria
Published 2022“…<h3>Background</h3><p dir="ltr">Gender-based violence (GBV) has been identified to be one of the ripple effects of the global pandemic. …”
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A Gendered Approach to Sectarianism
Published 2024“…Gender-responsive legislations proved to be effective in European consociational systems such as in Switzerland and Belgium, where women reached a significant level of substantial equality. …”
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Gender differences in personal values
Published 2015“…Design/methodology/approach – Based on a sample of 137 participants, the Kruskal-Wallis test was used to identify if the mean scores or ranks of personal values scores were significantly different between males and females. …”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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Ethnic and gender differences in the use of DISCOVER
Published 2009“…The purpose of this study was to examine ethnic and gender differences in using DISCOVER, a performance-based assessment, for identifying gifted students from diverse ethnicities. …”
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What determines vacation leave? The role of gender
Published 2017“…However, they reveal significant implications of work arrangements (e.g., part-time work, flexible work schedules, and home-based work), job promotion, supervisory tasks, and union membership for vacation use, for both men and women. …”
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