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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Discover: across the spectrum of grades
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Effectiveness of Concept Mapping: A Constructivist based Educational Strategy on Grade Seven Arab Students' Academic Achievement in Chemistry
Published 2016“…The participants were 64 grade seven students in a K-12 British curriculum private school in Dubai, the United Arab Emirates. …”
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The Effectiveness of Teaching Reading (Meta) Cognitive Strategies in Improving UAE Grade-12 Students’ Reading Comprehension Proficiency for School-based Tests and University Admiss...
Published 2015“…This study seeks to investigate the effectiveness of strategy-based instruction in improving the reading comprehension proficiency of the UAE grade twelve students in school-based tests and university admission exams like IELTS, TOEFL and CEPA after serious problems regarding reading comprehension have been reported, and many reform procedures have been taken to rectify these problems at university and pre-university levels. …”
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AI-Based Multiclass Grading of Hepatic Steatosis From B-Mode Ultrasound: Generalization Across Modalities and Clinical Comparison With Radiologists
Published 2025“…<p dir="ltr">Non-alcoholic fatty liver disease (NAFLD) is a growing public health challenge, underscoring the need for scalable, non-invasive tools to grade hepatic steatosis. Although B-mode ultrasound is accessible and safe, its reliability is limited by operator and scanner variability. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …”
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Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis
Published 2020“…Dipeptidyl peptidase-4 inhibitors (DPP-4i) led to a significant reduction in Hb<sub>A1c</sub> (%) (SMD -0.25) and a non-significant decrease in weight (kg) (SMD -1.06) during Ramadan. …”
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Single-cell analysis revealed high RFX6 expression levels in endocrine clusters across various hESC-derived pancreatic differentiation stages. Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …”
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The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis
Published 2020“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”