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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A hybrid graph representation for exact graph algorithms
Published 2014“…We investigate practical implementation-based aspects of exact graph algorithms by providing a simple hybrid graph representation that trades space for time to address the said take-back challenge. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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GDLL: A Scalable and Share Nothing Architecture Based Distributed Graph Neural Networks Framework
Published 2022“…The base layer utilizes an optimized distributed file system and a scalable graph data store to reduce the performance penalty. …”
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Oral contraceptive pills and possible adverse effects
Published 2014“…Since their introduction to the market, there have been significant changes in the drug content and formulations of these products, in part to decrease the risk of adverse effects. …”
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Applying Graph Neural Networks to the Decision Version of Graph Combinatorial Optimization Problems
Published 2023“…On top of this, we propose a new structure that is based on graph isomorphism networks. Computational experiments show that this new structure is significantly more efficient than basic structures. …”
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On the disk dimension of planar graphs
Published 2011“…More significantly, we devise a direct and highly practical linear-time algorithm to decide whether an arbitrary graph has fixed disk dimension k or less. …”
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EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
Published 2020“…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …”
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Domain Adaptation with Adversarial Training and Graph Embeddings
Published 2018“…We propose a novel model that performs adversarial learning based domain adaptation to deal with distribution drifts and graph based semi-supervised learning to leverage unlabeled data within a single unified deep learning framework. …”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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EEG-Based Multi-Level Mental State Classification Using Partial Directed Coherence and Graph Convolutional Networks: Impact of Binaural Beats on Stress Mitigation
Published 2025“…This study addresses limitations in EEG-based stress detection research by developing a novel approach to differentiate multiple mental states in different stress baseline population samples. …”
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Multi-IsnadSet MIS for Sahih Muslim Hadith with chain of narrators, based on multiple ISNAD
Published 2024“…Traditionally, scholars have focused on identifying the longest and shortest Sanad between two Narrators, but in MIS, the emphasis shifts to determining the optimum/authentic Sanad, considering narrator qualities. The graph representation of the authentic and manually curated dataset will open ways for the development of computational models that could identify the significance of a chain and a narrator. …”
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Supporting secure dynamic alert zones using searchable encryption and graph embedding
Published 2023“…We focus on a prominent SE technique in the public-key setting–hidden vector encryption, and propose a graph embedding technique to encode location data in a way that significantly boosts the performance of processing on ciphertexts. …”