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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
Published 2016“…There were significant differences between the groups in postoperative histology, with an increase in pathological stage III and TRG 4–5 in the R1 group. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Increased levels of CSF total but not oligomeric or phosphorylated forms of alpha-synuclein in patients diagnosed with probable Alzheimer’s disease
Published 2017“…CSF total α-syn (t-α-syn) significantly increased in the AD group (p < 0.0001) compared to controls, while oligomeric- and phosphorylated-Ser129-α-syn did not change significantly. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases
Published 2010“…Chemotherapy including bevacizumab was associated with a significantly higher frequency of complete or major response in both SD and LD groups. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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The Global Economic crisis & organisation change: case studies in the UAE
Published 2009“…Much of the restructuring took place under the banner of increasing corporate financial performance, but a significant byproduct of the deep-rooted organisational change it involves is additional strain on the organisation’s relationship with employees, communities, taxpayers, governments & stakeholders (Heugens, P., Schenk, H. 2004). …”
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Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study
Published 2024“…As well as an increase in happiness level among the study group compared to the control group were found (pre = 54.23 (6.60), immediate = 62.05 (4.09), post three-month = 61.95 (4.38), with statistical significant= <0.001 and effect size = 0.677.…”
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HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction
Published 2021“…A comparison between diabetic patients with penile prosthesis implantation infection and those without infection revealed no significant difference in the level of haemoglobinA1c between the two groups with mean haemoglobinA1c in patients with infected implants 7.14 and 7.59 for noninfected (<i>p</i> = 0.491). …”
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Percutaneous coronary intervention can be safely performed with left ventricular thrombus without increasing stroke risk: A 5-year retrospective review using real-world data
Published 2023“…Similarly, in-hospital mortality, all-cause mortality, and stroke at 12 months did not differ between the study groups.</p><h3>Conclusion</h3><p dir="ltr">Performing CAG +/− PCI among patients with LVT was not associated with an increased risk of stroke during admission or within 12 months in comparison to patients who did not undergo CAG +/− PCI, which may reassure cardiologists to perform CAG +/− PCI among patients with LVT safely.…”