A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

Examining the perceptions and practices of undergraduate dental students and facilitators about Problem-based Learning (PBL) instructional approach in the United Arab Emirates by MOHAMED -ZAIN, AMAL

“…One sample T test for the gender responses were T = - 0.620 and P-value = 0.535 showed no significant difference while One-way ANOVA were T = 4.518 and P-value = 0.001 found significant different between study level in problem-based Learning, ordered, as expected, as follows: Year 5 > Year 4 > Year 3 = Year 2 = Year 1. …”
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Environment, Education, and Personality Innovation Based Index by Al Qawasmi, Mahmoud Ghandi Mahmoud

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The Impact of Inquiry based Learning and Explicit Instruction of the Nature of Science on Students’ Views of the Nature of Science by HAWASH, WAEL ABOU

“…Similarly, all groups were taught the same science lesson i.e. same scientific concepts however as the research suggested with different techniques namely inquiry based, explicit instruction, and inquiry and explicit while the control group through direct instruction rote learning. …”
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Nomograph derivation for underwater sour gas releases in shallow waters based on computational fluid dynamics simulations by Wafa Imran (22046537)

Protecting Private Attributes in App Based Mobile User Profiling by Imdad Ullah (18372291)

“…In this work, we propose an app-based profile obfuscation mechanism, ProfileGuard, with the objective of eliminating the dominance of private interest categories (i.e. the prevailing private interest categories present in a user profile). …”

Recent advances in cobalt based heterogeneous catalysts for oxygen evolution reaction by Afreenuzzaman Badruzzaman (17115631)

“…Noble metal-based catalysts are the state-of-the-art catalyst used for OER currently. …”

ML-Based Handover Prediction and AP Selection in Cognitive Wi-Fi Networks by Muhammad Asif Khan (7367468)

Set-based approach for efficient evaluation and analysis of XACML policies. (c2014) by Jebbaoui, Hussein M.

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Effect of Strain Fields on Frequency Band Gaps of Periodic Lattice-Based Metamaterials by Shendy, Mohamed

“…Lattice-based metamaterials, known for their ability to deliver unique acoustic properties such as wave band gaps and direction-dependent phase velocities, are considered promising for noise filtering and acoustic sensor applications. …”
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A Novel Versatile Framework for Enabling Early Detection of Evolving Network-based Cyberattacks by THOMAS, RAJESH

“…Network-based cyber-attacks have been increasing in scale, frequency and sophistication, posing significant threats to nation states and organizations worldwide. …”
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Key determinants of SMEs’ export performance: a resource-based view and contingency theory approach using potential mediators by Arsalan Safari (10300058)

“…</p><h3>Design/methodology/approach</h3><p dir="ltr">This study draws on contingency theory and takes a resource-based and market-based view to provide a holistic understanding of the issue. …”