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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity
Published 2023“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System
Published 2013“…The reverse osmosis (RO) brine generated from the Al-Quds University wastewater treatment plant was treated using an epuvalisation system. …”
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
Published 2018“…Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …”
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Growth hormone treatment modulates active ghrelin levels in rats
Published 2014“…Genotropin treatment caused a dose dependent decrease in active ghrelin concentration in stomach, kidney and pancreas with a concomitant increase in plasma, and reaching significance at 20 and 100 µg/rat/day doses. …”
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Multilayer Reversible Data Hiding Based on the Difference Expansion Method Using Multilevel Thresholding of Host Images Based on the Slime Mould Algorithm
Published 2022“…This is because placing data in an image can cause permanent distortion after data mining. Therefore, a reversible data hiding (RDH) technique is required. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The impact of maternal care on child development
Published 2019“…Studying heterogeneous effects reveals a differential impact by child's age. An increase of 6.5 h per week in the time 2-year-olds spend with their mothers significantly improves their non-cognitive skills.…”
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The Impact of Employee Engagement on Turnover Intention and Burnout
Published 2021“…For instance, when employees are engaged with their work, their turnover intentions and burnout levels decrease. Accordingly, it is important to shed light on factors that can strengthen the positive impact of employee engagement in reducing turnover intention and burnout of employees. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Results indicate that AuNPs treatment significantly impacted several metabolic pathways. Notably, there was an increase in sphingomyelin (SM 34:2) levels (estimate 0.23, <i>p</i> ≤ 0.001), which are critical for cell membrane structure and signalling. …”
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EEG-Based Semantic Vigilance Level Classification Using Directed Connectivity Patterns and Graph Theory Analysis
Published 2020“…The strength and directionality of information flow in the connectivity network by RWTE/PDC and the GTA measures significantly decrease with vigilance decrement, p<0.05. …”
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Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response
Published 2019“…Paired <i>t-</i>test analysis of 22 locally advanced breast cancer patients showed that plasma NRP-1 levels were increased significantly (<i>p</i> = 0.018) post-NAC in patients with pathological partial response (pPR). …”
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Renewable Energy, Coal as a Baseload Power Source, and Greenhouse Gas Emissions: Evidence from U.S. State-Level Data
Published 2017“…After accounting for the role of coal as a baseload power source, an increase in the share of renewable energy is estimated to mitigate N2O emissions at the U.S. state level only if states individually decrease their share of coal use to levels below 41.47%. …”
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Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies
Published 2023“…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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The differential impact of IFRS adoption on aspects of seasoned equity offerings in the UK and France
Published 2018“…As a result of the lower levels of earnings management and information asymmetry, we predict and find that the market reaction to issuing SEOs improves significantly for high-divergence firms following IFRS. …”
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The Impact of the 2019 Lebanese Multidimensional Crisis on Young Adults’ Political Attitudes and Behavior
Published 2022“…Findings show that the 2019 multidimensional crisis had a significant negative impact on young adults’ political attitudes and behavior, affecting their affiliations, political interest, and trust. …”
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3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios
Published 2020“…Moreover, the use of an alternative concrete mixture in 3DCP showed a further decrease in the GWP, AP, EP, and FFD impact. Ultimately, the findings in this paper support the advantages of 3DCP technology and recommend the investigation of the development of (i) sustainable printable concrete materials and (ii) novel reinforcement techniques that are suitable for 3DCP rather than adopting conventional reinforcement techniques.…”
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