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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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3D printing of circular materials: Comparative environmental analysis of materials and construction techniques
Published 2023“…Life Cycle Assessment (LCA) was carried out for three cases of CDW-based 3D printed structures, Portland cement-based 3D printed structures, and conventional masonry construction methods and materials, to analyze the environmental impact of CDW-based 3D-printed designs and their comparative analysis. …”
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Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
Published 2023“…</p><h3>Method </h3><p dir="ltr">A retrospective study with 1303 cases of AA is performed. We compared the correlation of AAS and Alvarado scores to postoperative histopathology. …”
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3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios
Published 2020“…The LCA analysis showed that 3DCP significantly reduced environmental effects in terms of global warming potential (GWP), acidification potential (AP), eutrophication potential (EP), smog formation potential (SFP), and fossil fuel depletion (FFD), as compared to conventional construction methods. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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An investigation of the United Arab Emirates’ Performance and Progress on PISA Assessments: A Comparative Analysis of Multiple Case Studies
Published 2023“…This study employs a comparative approach to analyse multiple case studies, using quantitative methodologies and relying on secondary data sources. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Evaluating chemiluminescent immunoassays for syphilis detection: A comparative analysis
Published 2025“…BackgroundSyphilis, caused by Treponema pallidum (TP), remains a significant global public health concern, with approximately 8 million new cases annually. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Clinical and radiographic outcome of a bioceramic sealer compared to a resin-based sealer: a retrospective study
Published 2025“…BC and RB sealers revealed comparable clinical and radiographic outcomes with high success rates. …”