Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

OutPyR: Bayesian inference for RNA-Seq outlier detection by Edin Salkovic (16891479)

“…Existing solutions either require a large number of samples or do not provide proper statistical significance testing.</p><p dir="ltr">We present a Bayesian model (OutPyR) for identifying abnormal RNA-Seq gene expression counts in datasets, particularly those with a small number of samples. …”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Therapeutic and diagnostic applications of exosomal circRNAs in breast cancer by Mohanraj Gopikrishnan (17773449)

“…<p dir="ltr">Circular RNAs (circRNAs) are regulatory elements that are involved in orchestrating gene expression and protein functions and are implicated in various biological processes including cancer. Notably, breast cancer has a significant mortality rate and is one of the most common malignancies in women. …”

Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting by Shimaa Sherif (12862990)

“…</p><h3>Methods</h3><p dir="ltr">We developed a multi-step process to identify immune-related long non-coding RNA signatures with prognostic connotation in multiple TCGA solid cancer datasets.…”

Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke by Ghulam, Jeelani Pir

“…These pathways are crucial for cellular function and stress response, and their dysregulation can have significant implications for the disease processes. …”
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke by Ghulam Jeelani Pir (13914063)

“…These pathways are crucial for cellular function and stress response, and their dysregulation can have significant implications for the disease processes. …”

microRNA 21 and long non-coding RNAs interplays underlie cancer pathophysiology: A narrative review by Roberta, Giordo

“…Non-coding RNAs (ncRNAs) are a diverse group of functional RNA molecules that lack the ability to code for proteins. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”

MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the... by Radhakrishnan Vishnubalaji (3563306)

Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition by Ramesh Elango (7542068)

“…<h3>Background</h3><p dir="ltr">DNA methylation plays a crucial role in multiple cellular processes such as gene regulation, chromatin stability, and genetic imprinting. …”

Pharmacological interventions targeting β-adrenoceptors in colorectal cancer: an evolving paradigm by Aya Ghosn (22997230)

The multiomics analyses of cancer stem cells isolated from solid tumors can provide insight for their immunological characterization. by Neha Gopinath (15431052)

“…The nCounter platform (Nanostring) was utilized to assess the hybridization with 800 probes for miRNAs and the RNA seq-based transcriptomic profile (Lexogen) was also assessed.…”