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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Identifying the Inherent Factors Causing Delays in the UAE Construction Industry
Published 2021Get full text
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Optimization of p-chart for Processes with Multiple Assignable Causes and Random Shift
Published 2020Get full text
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd...
Published 2021“…NMR and U5MR were generally higher in males than in females, although there was no statistically significant difference at the global level. Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Unsustainability in emergent systems
Published 2017“…We propose a framework of corresponding mitigation options as a roadmap for improving the sustainability of the system, namely by reducing the reliance on fossil fuels, decreasing pollutants and Greenhouse Gas (GHG) emissions, reducing mobility costs and increasing passenger safety.…”
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Invasive Milk Thistle (Silybum marianum (L.) Gaertn.) Causes Habitat Homogenization and Affects the Spatial Distribution of Vegetation in the Semi-Arid Regions of Northern Pakistan
Published 2022“…The community composition significantly changes with changes in invasion intensity. …”
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A Double Dwell Frequency Synchronization Scheme For OFDM Systems
Published 2015Get full text
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A Survey of Indoor Localization Systems for Multi-Floor Environments
Published 2025“…As a result, multi-floor localization systems capable of identifying the user’s floor as well have recently gained significant attention. …”
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Learning-Based Spectrum Sensing and Access for Cognitive Radio Systems
Published 2015Get full text
doctoralThesis