-
1
-
2
-
3
-
4
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
5
The use of multi-task learning in cybersecurity applications: a systematic literature review
Published 2024“…This paper outlines various models utilized in the context of multi-task learning within cybersecurity and presents several challenges in this field.…”
-
6
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
7
-
8
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
-
9
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
Get full text
Get full text
Get full text
article -
10
-
11
Deep Learning in LncRNAome: Contribution, Challenges, and Perspectives
Published 2020“…<p dir="ltr">Long non-coding RNAs (lncRNA), the pervasively transcribed part of the mammalian genome, have played a significant role in changing our protein-centric view of genomes. …”
-
12
Medical and Health Sciences Librarians: New roles and challenges
Published 2024“…In addition to traditional library tasks, these specialized librarians contribute significantly to improving health outcomes by facilitating access to vital information and supporting evidence-based practice. …”
-
13
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
Get full text
Get full text
Get full text
article -
14
-
15
Implementing a collaborative care model for child and adolescent mental health in Qatar: Addressing workforce and access challenges
Published 2024“…<p>Child and adolescent mental health disorders in Qatar remain significantly underserved due to a critical shortage of specialists, stigma, and logistical barriers. …”
-
16
Navigating Anti Money Laundering Complexities: Evidence from the UAE
Published 2024Get full text
doctoralThesis -
17
Zooming Into Clarity: Image Denoising Through Innovative Autoencoder Architectures
Published 2024“…The ResoFocus Autoencoder is designed to optimize and denoise upsized images, while the FragmentumZoom Autoencoder targets small image segments to enhance denoising tasks. Empirical evaluations on diverse datasets, including CelebA and Autism Face data, demonstrate significant improvements in the Peak Signal-to-Noise Ratio (PSNR) and Structural Similarity Index Measure (SSIM). …”
-
18
Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection
Published 2024“…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…”
-
19
Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
Published 2023“…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. …”
-
20
Agent Productivity Modeling in a Call Center Domain Using Attentive Convolutional Neural Networks
Published 2020“…Measuring the productivity of an agent in a call center domain is a challenging task. Subjective measures are commonly used for evaluation in the current systems. …”
Get full text
Get full text