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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Conclusions</h3><p dir="ltr">We show that our network differencing procedure can effectively and efficiently detect statistical significant network re-wirings in different conditions. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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How effective are synthetic attack models to detect real-world energy theft?
Published 2025“…However, available datasets lack annotated real anomalies, which poses significant challenges in developing effective detection systems. …”
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Advanced nutrient monitoring: Cost-effective cerium ion detection with smart device integration
Published 2024“…Additionally, a cost-effective paper-based sensor and a portable colorimetric method for detecting cerium ions were innovatively designed. …”
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Advanced nutrient monitoring: Cost-effective cerium ion detection with smart device integration
Published 2024“…Additionally, a cost-effective paper-based sensor and a portable<u> colorimetric method</u> for detecting cerium ions were innovatively designed. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Diagnostic accuracy of interleukin-6 (IL-6) as a significant biomarker in late-onset neonatal sepsis: an updated systematic review and meta-analysis
Published 2025“…Subgroup and sensitivity analyses confirmed the robustness of the findings, and no significant threshold effect was detected. However, suspected publication bias was noted. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Accelerating Sepsis Diagnosis Through Culture-Free Genomics: Early Findings And Cost-Effectiveness From A Pilot Study
Published 2025“…This pilot study evaluated the feasibility and utility of Oxford Nanopore Technology (ONT) 16S rRNA sequencing, coupled with the EPI2ME 16S QULSS2025 workflow, for real-time pathogen detection directly from blood samples, alongside a cost-effectiveness assessment. …”
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Ensemble deep learning for brain tumor detection
Published 2022“…The analysis and mining of these data significantly influence the prediction, monitoring, diagnosis, and treatment of tumor disorders. …”
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Creating and detecting fake reviews of online products
Published 2022“…The model was also effective on detected human generated fake reviews. …”