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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Effect of fasting on laryngopharyngeal reflux disease in male subjects
Published 2012“…Subjects were considered to have LPRD if either the RSI or the RFS were positive (>9 RSI, >7 RFS). There was a non-significant increase in the total prevalence of LPRD while fasting compared to non-fasting (32 vs. 50 % while fasting, p value 0.361). …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Clinical, biochemical, and hematological characteristics of community‐dwelling adolescent and young adult males with anorexia nervosa
Published 2021“…A significant proportion of males with AN had traumatic bone fractures.…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Impact of body composition analysis on male sexual function: A metabolic age study
Published 2023“…Significantly lower T levels (p=0.002), significantly older MetAge (p=0.034), and higher BMI (p=0.044) and degree of obesity (p=0.042) were observed in participants <40 years with erectile dysfunction (ED) compared to their counterparts without ED.…”
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Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?
Published 2019“…When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. …”
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Sugar-Sweetened Beverages Contribute Significantly to College Students’ Daily Caloric Intake in Jordan: Soft Drinks Are Not the Major Contributor
Published 2019“…Anthropometric measurements of the participants including body weight, height, and waist circumferences were recorded. Male students consumed more calories from SSBs compared to female students (p = 0.016). …”
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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
Published 2020“…All analyzed CpGs in the sperm rDNA transcription unit show comparable age‐related methylation changes. Unlike other epigenetic aging markers, the rDNA clock appears to operate in similar ways in germline and soma in different mammalian species. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The effect of a sand surface on physical performance responses of junior male handball players to plyometric training
Published 2020“…<h2>Background</h2><p dir="ltr">The effects of 7 weeks plyometric training on a stable surface and on sand were compared in junior male handball players.</p><h2>Methods</h2><p dir="ltr">A team of experienced players was divided randomly between three groups, undertaking a standard in-season regimen (C, <i>n</i> = 10), or supplementing this regimen by plyometric training on sand (PS, <i>n</i> = 11) or a stable surface (P, n = 10) for 7 weeks. …”
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Differences in Player Position Running Velocity at Lactate Thresholds Among Male Professional German Soccer Players
Published 2019“…The running data revealed that only goalkeepers had significantly lower velocities at the lactate thresholds compared to outfield players. …”
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A genome-wide transcriptomic analysis of embryos fathered by obese males in a murine model of diet-induced obesity
Published 2022“…To this end, we investigated whether paternal obesity is associated with gene expression changes in eight-cell stage embryos fathered by males on a high-fat diet. We used single embryo RNA-seq to compare the gene expression profile of embryos generated by males on a high fat (HFD) versus control (CD) diet. …”
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Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system
Published 2023“…Differentially expressed proteins were used for KEGG and WIKIpathway annotation to determine pathways in which the proteins of interest were significantly over-represented.</p><h3>Results and conclusion</h3><p dir="ltr">Autoantibody responses to 57 proteins were significantly altered in the COVID-19 Disc cohort compared to healthy controls (p ≤ 0.05). …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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