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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Anthracyclines-Induced Vascular Endothelial Dysfunction in Cancer Patients and Survivors Using Brachial Flow-Mediated Dilation (FMD) Tool: A Systematic Review and Meta-Analysis
Published 2025“…Compared to the baseline, a non-significant change toward a decline in FMD was observed. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention
Published 2023“…This study also found significant evidence for serial mediation by POS on PGST and its relationship with turnover intention. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The Impact of Leadership Styles on Improving Employee Agility: The Mediating Role of Employee Incentives
Published 2024“…Analyses of the direct relationships suggest that transformational leadership style has a significant impact on employee agility. While analysis of the indirect relationships confirms that employee incentives is a significant mediator for the relationship of transactional and laissez-faire leadership with employee agility however, years of experience does not have a moderating role for any of the above relationships. …”
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Audit committee chair effectiveness and firm performance: The mediating role of sustainability disclosure
Published 2023“…Furthermore, the findings revealed that sustainability disclosure mediates the relationship between AC chair effectiveness and ROE in part. …”
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Cytosolic Phospholipase A2-Mediated ICAM-1 Expression Is Calcium Dependent
Published 2001“…Groups were compared using ANOVA with Scheffe's post hoc analysis; *P < 0.05 vs control, †P < 0.05 vs LPS and TNF-α was considered significant; N ≥ 4 all experimental groups. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The Effects of Dynamic Assessment and its Mediating Factors on EFL Twelfth Graders’ Grammar Achievement in the UAE
Published 2023“…While quantitative data have been analyzed using descriptive and inferential statistics, including independent sample t-test, one-way ANOVA, two-way ANOVA, and post-hoc multiple comparisons, qualitative data have been analyzed using thematic analysis. Based on the results of the study, there is a significant effect of DA on the level of grammar achievement for EFL twelve graders for the experimental group that has undertaken the DA intervention compared to the NDA group. …”
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The Mediation Roles of Coping Modalities on the Relationship Between Stress and Quality of Life Among Jordanian Nurses
Published 2024“…The results showed that coping significantly mediated the relationship between stress and QOL with variations between PFC and EFC. …”
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