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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A component analysis of positive behaviour support plans
Published 2012“…Background Positive behaviour support (PBS) emphasises multi-component interventions by natural intervention agents to help people overcome challenging behaviours. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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The mediating effect of Work Engagement on the relation between Career Adaptability and OCB
Published 2020“…Results indicated that career adaptability has significant positive influence on OCB and work engagement, work engagement in turn is positively associated with OCB and acted as a partial mediator for career adaptability and OCB. …”
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Audit committee chair effectiveness and firm performance: The mediating role of sustainability disclosure
Published 2023“…The findings revealed a significant and positive relationship between the accounting expertise, tenure, and monitoring expertise of the AC chairs and the performance of the firm measures tested, namely, ROA and ROE. …”
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Investor sentiment and stock price crash risk: The mediating role of analyst herding
Published 2024“…Furthermore, stock price crash is positively correlated with analyst herding i.e. it significantly mediates between stock price crash risk and investor sentiment. …”
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The mediating effect of organisational resilience and internal preparedness on the relationship between external vulnerabilities and performance
Published 2024“…The relationships between resilient characteristics, resilient capacities, and firm performance were also positive and significant. The mediation results showed an indirect relationship between resilient characteristics and firm performance, and resilient capacities fully mediated this association. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The Effects of Dynamic Assessment and its Mediating Factors on EFL Twelfth Graders’ Grammar Achievement in the UAE
Published 2023“…The present study investigates the effects of dynamic assessment (DA) and its mediating factors on EFL twelve graders’ grammar achievement in a private school in Dubai, UAE. …”
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Achieving the sustainable development goals in developing countries: The role of remittances and the mediating effect of financial inclusion
Published 2024“…Utilizing data from 109 developing countries spanning 2000 to 2022 and employing system GMM and the Lewbel's (2012) estimator to tackle endogeneity issues, we unveil significant positive effects of remittances on SDGs. …”
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The Impact of Transformational Leadership on Employee Productivity, Happiness, and Burnout: The Mediating Role of Employee Engagement and Stress
Published 2024“…Both EE and JS significantly mediate the relationships between TL and EP, HAW, and JB. …”
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