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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Interval-Valued Reduced Ensemble Learning Based Fault Detection and Diagnosis Techniques for Uncertain Grid-Connected PV Systems
Published 2022“…The IKPCA-EL techniques are addressed so that the features extraction and selection phases are performed using the IKPCA models and the sensitive and significant interval-valued characteristics are transmitted to the EL model for classification purposes. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Variation of Shear Wave Velocity with SPT-N Values in the City of Sharjah
Published 2014Get full text
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Performance Prediction Using Classification
Published 2019“…Interestingly the variance in the performance measure values are not very significant for some of the models and it can be concluded that early risk prediction can happen earlier in the semester when intervention and associated benefits of improving student performance is more probable.…”
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The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention
Published 2023“…This study also found significant evidence for serial mediation by POS on PGST and its relationship with turnover intention. …”
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A Diffusion-Based Probabilistic Ultra-Short-Term Solar Power Prediction Using the Sky Image Sequences
Published 2025“…<p dir="ltr">The inherently unpredictable nature of solar power generation, primarily due to rapidly changing cloud cover, poses a significant challenge to the operation of solar-integrated energy systems. …”
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The effect of CEO ownership & CEO entrenchment on firm value. (c2011)
Published 2011Get full text
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Prediction of evaporation losses in wet cooling towers
Published 2020“…An empirical relation is developed on the basis of ASHRAE’s rule of thumb that is simple and accurate with a wide range of applicability. The predicted values are in good agreement with experimental data as well as predictions made by an accurate mathematical model.…”
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