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The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…Furthermore, limited evidence showed that lost body weight may be primarily due to fat mass reduction. Tirzepatide also significantly decreased food intake, reduced overall appetite scores and increased fasting visual analog scale scores for satiety and fullness across different clinical trials. …”
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Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection
Published 2024“…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…”
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3
Chemical characterization and cytotoxic activity evaluation of Lebanese propolis
Published 2017“…Toxicity started early after 24 h of incubation and remained till 72 h. Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …”
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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masterThesis -
5
Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition
Published 2025“…Finally, our results revealed a significant decrease in the ratios of P-ERK/ERK and P-MEK/MEK following treatment. …”
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masterThesis -
6
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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masterThesis -
7
Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …”
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masterThesis -
8
Assessment of Brain Function After 240 Days Confinement Using Functional Near Infrared Spectroscopy
Published 2024“…The FCN shows a significant decrease in most of the right frontal areas. …”
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Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules
Published 2020“…Finally, A375 cells treated with curcumin and the nanocapsules showed a significant increase in single- and/or double-strand DNA breaks upon exposure to light, indicating promising biological effects.…”
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The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. …”
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The Effect of Treated Waste-Water on Compaction and Compression of Fine Soil
Published 2016“…The maximum dry unit weight increased for both soils and the optimum water content decreased as much as 13.6% for highly plastic soil. …”
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Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes
Published 2010“…The addition of SRHA caused the boron nanoparticles to stabilize and resulted in (1) decreased attachment efficiency for the reaction-controlled regime and (2) an increase in the critical coagulation concentration, in CaCl2 and MgCl2 solutions. …”
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Metformin treatment inhibits motility and invasion of glioblastoma cancer cells
Published 2018“…The results show a significant decrease in the survival of SF268 cancer cells in response to treatment with metformin. …”
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Extraction and characterization of biofunctional lignocellulosic fibers from Pulicaria undulata plant and the effect of alkali treatment on their bio-physicochemical properties
Published 2024“…In contrast, alkali-treated fibers showed a significant decrease in radical scavenging activity (almost 7–8 fold) and reducing power potential (6-fold) and exhibited no antifungal activity, potentially due to the loss of bioactive components such as lignin and essential oils. …”
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Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System
Published 2013“…The increasing of channel number or closed loop time is estimated for enhancing the treatment process and increasing the nutrient uptake. …”
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Carbon Nanotube Effect on the Ductility, Flexural Strength, and Permeability of Concrete
Published 2019“…Furthermore, the results showed that CNTs would increase the ductility of concrete beams by about 150%. …”
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Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
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doctoralThesis -
18
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
Published 2022“…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …”
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Following <i>LDHC</i> knockdown, we observed an increase in the secretion of tumor-derived pro-inflammatory cytokines (IFN-γ, GM-CSF, MCP-1, CXCL1), a decrease in the soluble levels of tumor-derived immunosuppressive factors (IL-6, Gal-9) and reduced tumor cell surface PD-L1 expression. …”
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20
Zirconium Silicate/IL/Mxene-based composite membranes for high-temperature fuel cell applications
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doctoralThesis