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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Total and segmental liver volume variations
Published 2015“…This reproducible, noninvasive procedure is necessary because significant interpatient variation is believed to exist in the relative contributions of the hepatic segments to TLV.11 CT volumetry accurately predicts TLV on the basis of body surface area or body weight,12 which may achieve the true goal of preoperative CT volumetry of the liver, that is to estimate the individual patient's hepatic metabolic demands after resection or transplantation.7 Complications associated with technical aspects of liver surgery are decreasing, and focus has concurrently shifted to analysis of postoperative complications after major hepatic resection and liver transplantation on the basis of liver remnant volume and graft volume.3., 4., 6., 7., 8. and 13. …”
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Variational Auto Encoder Approach To Find Deferentially Expressed Genes
Published 2022“…In this paper, I proposed a framework that is based on a variational autoencoder called BiDiffVAE (Bi-directional Differential Variational Autoencoder) to extract differently expressed genes. …”
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Linburg–Comstock variation and syndrome. A meta-analysis
Published 2017“…Introduction Linburg–Comstock variation often connecting the flexor pollicis longus and flexor digitorum profundus of the index finger at a different level with significant discrepancy between clinical and cadaveric frequencies reported in the literature. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Impact of Variation in Estimated Quantity Clauses on Allocating Financial Risks in Measurement Contracts
Published 2021“…Then the paper examines the impact of VEQ clauses on the distribution of financial risks associated with changes in quantities between the owner and the contractor. The paper shows significant inconsistencies between the terms and stipulations of variation in estimated quantity clauses adopted by different US public construction authorities and international construction contract forms. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus
Published 2023“…Using this approach, we observed high inter-individual variation in rDNA CN, and limited intra-individual copy differences in several post-mortem tissues. …”
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Procedural Variation in Pars Plana Vitrectomy for the Management of Rhegmatogenous Retinal Detachment: A Retrospective Cohort Study
Published 2025“…The final visual acuity showed a significant difference in the effect of ILM peeling with visual acuity better in patients who did not undergo ILM peeling at 0.52 ± 0.49 LogMAR. …”
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A population study of clinically actionable genetic variation affecting drug response from the Middle East
Published 2022“…The allele frequencies of 1,320 variants in 703 genes affecting 299 drugs or class of drugs were significantly different between the Qatari population and other world populations. …”
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Holocene relative sea-level variations and archeological implications, Abu Dhabi western region, United Arab Emirates
Published 2020“…New results from fieldwork in the western region of the Emirate of Abu Dhabi showed meaningful differences in relative sea-level variations during Holocene and recorded unknown late marine highstands. …”
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