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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
Published 2025“…Accurately identifying small defects on PCB surfaces remains a considerable challenge, particularly under complex background conditions, due to the intricate and compact layout of the boards. …”
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Additionally, the addition of vegetation alone had an impact on the microclimate decreasing it by 5%. Thus, combining the strategies of vegetation, shade, green facades/roofs and small water features resulted in 5% to 25% reduction in PET depending on the corresponding location being analyzed. …”
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Determinants of Off-Balance Sheet Business in the Case of GCC Banking Sectors during Covid-19
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Information Technology Disaster Recovery Plan (IT DRP) Framework – A study on IT Continuity for Smart City in Abu Dhabi Smart Government
Published 2017“…Similarly for businesses, it has boosted global communication, trade and development. However, the reliance on information technology has also increased the challenges with one such being disaster recovery. …”
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Examining the nexus of mineral resources, technology adoption, and economic expansion in advancing sustainable development in OECD economies
Published 2024“…The study highlights the dilemma of industrialized countries: the reliance on natural resources for economic growth versus the necessity of environmental conservation. …”
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Innovation Ecosystem for Resource-Rich Countries: Validation of Entrepreneurship Framework for Qatar as a Case
Published 2024“…The anticipated result is better policymaking in entrepreneurship, increased entrepreneurial activity and success, and a move away from reliance on traditional oil and gas sectors. …”
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The Impact of Capital Formation on Economic Diversification in GCC Countries—Empirical Analysis Based on the PVAR Model
Published 2023“…<p dir="ltr">Economic diversification has been a cornerstone of the policy agenda of resource-rich countries, such as Gulf Cooperation Council (GCC) countries, seeking sustainable economic development to avoid reliance on hydrocarbon revenues that cause significant vulnerabilities and economic, social, and political instability in the long term. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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Arsenic contamination in rice: a DPSIR analysis with a focus on top rice producers
Published 2025“…The DPSIR analysis revealed that socioeconomic factors, including population growth and industrialization, were the primary driving forces behind arsenic contamination in rice. These factors increased pressures such as reliance on arsenic-contaminated irrigation water, historical pesticide use, and industrial pollution, which contributed to arsenic accumulation in rice-growing environments. …”
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The Experience of Palliative Care Nurses in Qatar During the Time of COVID-19: A Qualitative Study
Published 2023“…These implications include (a) holding continuing education sessions to help nurses better understand the meaning of pandemic conditions and how best to respond and (b) supporting nurses to better cope with the additional burdens faced because of increased patient loads. Overall, the nurses in this study were shown to have demonstrated reliance and resilience in the face of COVID-19.…”