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decrease » increase (Expand Search)
interaction site » interactions _ (Expand Search), insertion sites (Expand Search), interactions a (Expand Search)
decrease » increase (Expand Search)
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
Published 2021“…In a continuous variable analysis, the association between 25(OH)D and bone mass was significant, non-linear, inverse ‘U’. In conclusion, serum 25-hydroxyvitamin D was inversely associated with adiposity measures and non-linearly associated to bone mass in postmenopausal Qatari women.…”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…Statistical Coupling Analysis (SCA) of GAF domain sequences identified these residues, and molecular dynamics (MD) simulations of both apo and holo forms of wild-type and mutant (L267A, F295A) PDE5 GAFa domains revealed significant changes in structural dynamics and cGMP interaction. …”
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Understanding the formation of active site in copper ceria system for carbon dioxide catalytic conversion
Published 2025“…The results suggest that Cu loading and calcination temperature in Cu/CeO<sub>2</sub> system could significantly enhance the presence of active sites for effective CO<sub>2</sub> hydrogenation.…”
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Malignant peritoneal mesothelioma interactome with 417 novel protein–protein interactions
Published 2024“…The MPeM interactome overlapped significantly with the malignant pleural mesothelioma interactome, revealing shared molecular pathways.…”
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In silico virtual screening of lead compounds for major antigenic sites in respiratory syncytial virus fusion protein
Published 2022“…These binders exhibited significant interactions with neutralizing epitopes on RSV F, with an average of six H bonds, docking energy of − 15.43 Kcal·mol−1, and minimum interaction energy of − 7.45 Kcal·mol−1. …”
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Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
Published 2025“…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …”
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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…Fifty-nine patients with both clinical evidence of thyroid dysfunction and patent diabetes mellitus were investigated in our diabetology department. …”
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Insights into the interaction between mineral formation and heavy metals immobilization, mediated by Virgibacillus exopolymeric substances
Published 2024“…In this study, the interactions between several selected heavy metals (Cd2+, Cu2+, Ni2+, Zn2+), EPS, and mineral formation were investigated using two mineral-forming Virgibacillus strains isolated from the Qatari sabkhas, which are known to be suitable sites for the formation of biominerals. …”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”
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Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…We aimed to describe the epidemiological and clinical characteristics of fall-related injuries in a level 1 trauma center.…”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging
Published 2001“…The children with white-matter abnormalities and decreased tone had significantly less signal intensity abnormality than the other study groups. …”
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Self-reported awareness and attitude of cancer patients towards clinical nurse coordinators
Published 2017“…Background and objective: Lack of knowledge or poor perception towards the roles and responsibilities of clinical nurse coordinators among cancer patients might lead to a decrease in seeking their services. …”
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Procrastination on social media: predictors of types, triggers and acceptance of countermeasures
Published 2021“…Several factors including personality, culture and gender have been identified as predictors of procrastination, although there are some conflicting findings within the literature. Social networking sites have been identified as a possible facilitator of procrastination, in part due to their design features that encourage immersion and continual interaction. …”