Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning by Noaman Khan (19810050)

“…Our numerical experiments show that this approach can potentially lead to a reduction in the cost of storing and applying sparse approximate inverse preconditioners, although a significant reduction in cost may comes at the expense of increasing the number of GMRES iterations required for convergence.…”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women by Vijay, Ganji

“…Serum 25(OH)D was significantly, inversely associated with body mass index (p < 0.0005), waist circumference (0.044), fat mass (p < 0.003), gynoid fat (p < 0.001), and android fat (p < 0.009). …”
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Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women by Vijay Ganji (8710491)

“…Serum 25(OH)D was significantly, inversely associated with body mass index (p < 0.0005), waist circumference (0.044), fat mass (p < 0.003), gynoid fat (p < 0.001), and android fat (p < 0.009). …”

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

“…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …”

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

“…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

Geopolitical instability and environmental sustainability by Dagar, Vishal

“…Panel quantile regression results show a significant relationship between increased geopolitical risk, ecological footprints, and carbon emissions, with coefficients ranging from 0.357 to 0.785 across quantiles in the case of ecological footprints and 0.939–1.961 for carbon emissions. …”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

“…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …”

Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro by Rizk, Sandra

“…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …”
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Investigating vulnerability for developing eating disorders in a multi-confessional population by Doumit, Rita

“…Affiliating as Christian was found to significantly decrease the vulnerability to developing an ED. …”
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Proteome analysis of Candida albicans cell wall mutants. (c2011) by Koussa, Joseph Wissam

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OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... by Pia Tohme Khalaf (17425551)

“…The couple's relationship quality also plays a significant role, with secure romantic attachment positively influencing prenatal attachment and promoting resilience in times of stress, while avoidant or anxious romantic attachment can lead to lower prenatal bonding and increased pregnancy-related worries.…”

Optimizing the Cleaning Frequency of Solar Photovoltaic (PV) systems Using Numerical Analysis by Kaiss, El-Cheikh Amer Kais

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Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample by Khazen, Georges

“…Being Christian was found to significantly decrease the vulnerability to developing an ED. …”
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