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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Significance of microscopically incomplete resection margin after esophagectomy for esophageal cancer
Published 2016“…There were significant differences between the groups in postoperative histology, with an increase in pathological stage III and TRG 4–5 in the R1 group. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
Published 2020“…Drug treatment in these cells significantly reduced cellular proliferation, viability, migration and increased apoptosis. …”
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Accessibility of large events: an empirical study of the Expo 2020 Dubai
Published 2024“…The objective of this paper is to contribute to understanding the accessibility of large events in an increasingly technology-dependent industry. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems
Published 2021“…The results also show that high speed chargers have a more significant impact than an increase in battery sizes of the EBs.…”
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Redefining global influence: The roles of small states – Norway and Qatar in the aftermath of the Russian-Ukraine war
Published 2025“…<p dir="ltr">Small states can significantly influence international relations, as seen in the cases of Qatar and Norway. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Adaptive response for climate change challenges for small and vulnerable coastal area (SVCA) countries: Qatar perspective
Published 2023“…Long-term mitigation efforts would not help them reduce their current or immediate vulnerability in the short-term, as long as large countries with comparably huge populations, economies, heavy industrial dependences, and extreme consumption levels do not change their courses significantly. …”
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Aerosol Optical Thickness over Large Urban Environments of the Arabian Peninsula—Speciation, Variability, and Distributions
Published 2019“…Over the past decade, the mean annual aerosol optical thickness (AOT) values were in the range of 0.3–0.5, which is attributed to both mineral dust (60–70%) and anthropogenic activities (20–30%). An increase in AOT values between 2005 and 2009 is attributed to increased dust generation from the Sahel region in Northern Africa, and the Fertile Crescent (Syria, Iraq, Jordan) due to an extended dry period. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Perinatal factors impacting echocardiographic left ventricular measurement in small for gestational age infants: a prospective cohort study
Published 2023“…<h2>Introduction</h2><p dir="ltr">Infants born small for gestational age (SGA) have an increased risk of developing various cardiovascular complications. …”