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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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An Analysis of the Common Grammatical Errors in the English Writing made by 3rd Secondary Male Students in the Eastern Coast of the UAE
Published 2008“…Furthermore, the findings and the results of this study also showed that the English writing skill of the secondary male students in the UAE state schools needs more reinforcement and development. Based on the findings, recommendations and some implications which are of significance to educators and policymakers as well as to EFL teachers are provided. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Unpacking the mechanisms of entrepreneurial bricolage for new venture growth: the mediating roles of new venture adaptiveness and innovative ambidexterity
Published 2024“…<p dir="ltr">Drawing upon the resource-based view of the firm, this article employs this perspective to examine how new venture adaptiveness and innovative ambidexterity mediate the relationship between entrepreneurial bricolage and new venture growth within Bangladesh’s Ready-Made Garment Industry. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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Special Issue: Empowering eHealth with Smart Internet of Things (IoT) Medical Devices
Published 2019“…</p><p dir="ltr">Q2 What important advances have been made to empower eHealth with novel IoT devices? </p><p dir="ltr">Q3 Has data interpretation and fusion improved significantly in recent years? …”
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An Alternative Setup for a Base-Station Cellular Antenna
Published 2007“…It is shown that for a sufficiently large attenuation pattern beyond the antenna beamwidth, the corresponding signal-to-interference ratio can be made significantly larger than the one resulting from the traditional antenna setup.…”
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Novel Natural Based Chewable Lozenges for the Treatment of Erectile Dysfunction
Published 2022“…Adjustments of the total liquid content was made to obtain a volume of 1.55 ml/lozenge and a water content of 0.30 ml/lozenge. …”
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A Blockchain-Based Scalability Solution with Microgrids Peer-to-Peer Trade
Published 2024“…This concept has been made possible by the emergence of blockchain technology, which has gained significant traction in the energy markets. …”
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Effect of Strain Fields on Frequency Band Gaps of Periodic Lattice-Based Metamaterials
Published 2024“…Lattice-based metamaterials’ unique acoustic abilities arise from their periodic porous structures, allowing them to be realized even when the lattices are made from isotropic materials. …”
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Novel platinum(II)-based anticancer complexes and molecular hosts as their drug delivery vehicles
Published 2007“…Encapsulation by CB[6] was found to not significantly change the cytotoxicity of five platinum(II)-based DNA intercalators, indicating it may have utility as a molecular carrier for improved drug delivery.…”
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