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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Customer Service and Satisfaction in the three main Airports of the United Arab Emirates
Published 2007“…Based on that, 5 main criteria were set that had to be met and continuously achieved by the aviation industry in the UAE. …”
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Detection of statistically significant network changes in complex biological networks
Published 2017“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. …”
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The Grid Iron Patterns & Detached Villas as the Main Drivers of Sharjah City’s Urban Sprawl
Published 2021“…On the other hand, the same study proved that the grid system and the villa model are the main reason behind the urban sprawl of the city. …”
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Enhancing the Main Contractor-Subcontractor trusting relationship in the United Arab Emirates: A strategic approach to rebuilding trust in complex construction projects
Published 2017“…The researcher found that trust factor has a significant impact on subcontractors and main contractors’ relationship, however, there is minor impact of their relationship on building trust between them, and that early contractor engagement in the initiation and planning stage positively impacts the subcontractors and main contractors’ relationship, and that the higher the level of trust between them, the better the project performance. …”
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Studying the impact of an energy retrofit of a UAE-based existing building by adding intelligent valves on the main chilled water risers and reconfigure the chilled water pumps to...
Published 2021“…With that being said, this research aims to provide reliable information and outputs on the best practice of operating chilled water network for a UAE-based building by converting the constant primary network to a variable one in addition to solve permanently the building ΔT issues by replacing the conventional pressure dependent control valves and adding intelligent valves on the main risers and the main airside equipment for this selected building, aiming to be quite practical as could as possible and have the outcome of combining both measures together, accordingly, the results show a potential energy saving on the range of 14-21% on the conservative side by applying the suggested retrofit measures, which leads to approximately an energy cost of savings of at least half a million to seven hundred thousands of UAE dirhams along with simple payback of 3-4 years which is considered an attractive SPB period for investors on such fields. …”
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
Published 2022“…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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The significance of general skills training for early career graduates: relationships with perceived organizational support, job satisfaction and turnover intention
Published 2023“…Analysis was conducted using partial least square-based structural equation modelling (PLS-SEM). Findings– The main finding is that participation in general skills training (PGST) does not directly impact turnover intention, rather POS is a mechanism through which this negative relationship operates. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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The Play-based Behaviours of Emirati Preschool Children: Cultural Perspective into Early Childhood Education
Published 2020“…The main objectives of this research were to provide insight into Emirati maternal values on play, to analyse behavioural factors, and to suggest policies that better support them. …”
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Examining the perceptions and practices of undergraduate dental students and facilitators about Problem-based Learning (PBL) instructional approach in the United Arab Emirates
Published 2018“…One sample T test for the gender responses were T = - 0.620 and P-value = 0.535 showed no significant difference while One-way ANOVA were T = 4.518 and P-value = 0.001 found significant different between study level in problem-based Learning, ordered, as expected, as follows: Year 5 > Year 4 > Year 3 = Year 2 = Year 1. …”
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Special Issue: Empowering eHealth with Smart Internet of Things (IoT) Medical Devices
Published 2019“…In such an environment, the patient’s vital parameters are transmitted by medical devices onto secure cloud based platforms where they are stored, aggregated and analyzed. …”