Search alternatives:
mediator » mediation (Expand Search), mediated (Expand Search), mediates (Expand Search)
increased » increase (Expand Search)
decrease » increase (Expand Search)
mediator » mediation (Expand Search), mediated (Expand Search), mediates (Expand Search)
increased » increase (Expand Search)
decrease » increase (Expand Search)
-
1
-
2
Cytosolic Phospholipase A2-Mediated ICAM-1 Expression Is Calcium Dependent
Published 2001“…Cytosolic phospholipase A2 (cPLA2) is a lipid-mediator activated by inflammatory stimuli, which has been shown to mediate ICAM-1 upregulation. …”
Get full text
Get full text
Get full text
article -
3
-
4
-
5
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
6
Serum immune mediators as novel predictors of response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients with high tissue-PD-L1 expression
Published 2023“…Moreover, correlation analysis showed significant positive linear correlation of soluble PD-L1 (sPD-L1) with higher TPD-L1 expression. …”
-
7
The combinatory effects of diet and exercise on BDNF gene expression
Published 2017“…On the other hand, exercise induces beneficial responses in the brain, many of which are mediated through induction of BDNF expression. Moreover, BDNF expression was shown to be enhanced under select dietary conditions. …”
Get full text
Get full text
Get full text
article -
8
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
9
-
10
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
-
11
Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine
Published 2020“…Interestingly, the expression of eNOS in the Cd-treated group was found to be significantly elevated during the exposure by more than 3-fold in comparison with that in the control group. …”
-
12
miRNA-dependent regulation of STIM1 expression in breast cancer
Published 2019“…The ER Ca<sup>2+</sup> sensor STIM1 and Orai plasma membrane Ca<sup>2+</sup> channels molecularly mediate SOCE. Here we investigate the role of the microRNA machinery in regulating STIM1 expression. …”
-
13
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
Get full text
Get full text
Get full text
article -
14
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Published 2018“…<p>Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. …”
-
15
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…The ratio of APN/leptin expression in VSMCs significantly decreased after 24 hours of mechanical stretch. …”
-
16
-
17
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
Get full text
Get full text
Get full text
article -
18
Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…In this study, we showed for the first time that arginine deprivation using a recombinant human arginase induces ferroptosis, an autophagy-mediated type of cell death in AML cells. Acute Myeloid Leukemia (AML) poses significant challenges due to its unfavorable prognosis and limited treatment options, particularly in elderly patients. …”
Get full text
Get full text
Get full text
masterThesis -
19
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi...
Published 2011“…Macrophages from ApoE⁻′⁻/TG-BM chimeric mice express reduced levels of PPARγ₁, LXRα, ATP-binding cassette A₁ (ABCA₁) and ATP-binding cassette G₁ (ABCG₁) and increased levels of the inflammatory mediators interleukin (IL)-6 and tumor necrosis factor (TNF)-α compared with macrophages of control chimeric mice (ApoE⁻′⁻/NT-BM) that received AEBP₁ nontransgenic (AEBP₁ᴺᵀ) BM cells. …”
Get full text
article -
20
Anti-hypertrophic effect of Na+/H+ exchanger-1 inhibition is mediated by reduced cathepsin B
Published 2020“…Moreover, Cat B protein expression and MMP-9 activity in the extracellular space were significantly attenuated in the presence of EMD or CA-074Me. …”
Get full text
Get full text
Get full text
article