Search alternatives:
one based » drone based (Expand Search), ni based (Expand Search), fe based (Expand Search)
decrease » increase (Expand Search)
one based » drone based (Expand Search), ni based (Expand Search), fe based (Expand Search)
decrease » increase (Expand Search)
-
1
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
2
-
3
-
4
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
-
5
-
6
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
-
7
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
8
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
Get full text
Get full text
Get full text
article -
9
-
10
Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene
Published 2004“…The GG genotype was also significantly higher among patients (12.6%) than in controls (4.2%). χ2 analysis and family-based association studies were performed and suggested the association of CTLA4 exon 1 G polymorphism with T1D (p = 0.0229). …”
Get full text
Get full text
Get full text
article -
11
Treating Cancers Using Nature’s Medicine: Significance and Challenges
Published 2021“…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
-
12
-
13
-
14
Detection of statistically significant network changes in complex biological networks
Published 2017“…The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”
-
15
Significance of Avicennia Marina in the Arabian Gulf Environment: A Review
Published 2025“…This review addresses the current knowledge gap by providing an overview of Avicennia marina distribution in the Gulf, exploring the significance of its ecosystem services, analyzing the impacts of stressors, and examining conservation and restoration efforts, with attention to nature-based and biotechnological approaches for promoting mangrove growth and conservation in the Gulf.…”
-
16
-
17
Dynamic Properties of Water Confined in Graphene-Based Membrane: A Classical Molecular Dynamics Simulation Study
Published 2019“…By decreasing the density of water molecules inside the membrane, we observed that water molecules form a droplet through a hydrogen bond with each other in the hydrophobic environment that stacked graphene sheets create. …”
-
18
Cluster-based anonymity model and algorithm for 1:1 dataset with a single sensitive attribute using machine learning technique
Published 2024“…An efficient Cluster Based anonymity model has been proposed to anonymizes the 1:1 dataset with a single sensitive attribute through the introduction of a concept named “Semi-sensitive attribute.” …”
-
19
Performance Evaluation of a New Fluorescent-Based Lateral Flow Immunoassay for Quantification of Hemoglobin A1c (HBA1c) in Diabetic Patients
Published 2023“…<h3>Background</h3><p dir="ltr">Rapid hemoglobin A1C (HbA1c) level monitoring is essential in slowing the progression of diabetes. …”
-
20
MACGAN: An All-in-One Image Restoration Under Adverse Conditions Using Multidomain Attention-Based Conditional GAN
Published 2023“…To address this, an all-in-one Multidomain Attention-based Conditional Generative Adversarial Network (MACGAN) is proposed to improve scene visibility for optimal ground, aerial, and marine navigation, using the same set of parameters across all domains. …”