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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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A hybrid model to predict the pressure gradient for the liquid-liquid flow in both horizontal and inclined pipes for unknown flow patterns
Published 2023“…<p dir="ltr">Accurate prediction of the pressure gradient (PG) for the oil-water flow requires identification of the flow pattern (FP), which is usually achieved by using either an expensive measurement system or time-consuming manual observations. …”
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition
Published 2025“…Unlike SKOV-3 cells, which demonstrated a decrease in E-cadherin and an increase in N-cadherin after treatment, the E-cadherin/N-cadherin profile in PA-1 treated cells exhibited an inverse pattern. …”
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Exploring the link between physical activity and professional quality of life among nurses: a cross-sectional study in Qatar
Published 2025“…Burnout showed no significant association with PA levels. Sociodemographic factors, including age and shift patterns, were associated with PA, with moderate PA being more common among slightly older nurses and those working 8-hour shifts.…”
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Numerical Investigation of the Fetal Left Heart Hemodynamics During Gestational Stages
Published 2021“…<p dir="ltr">Flow-driven hemodynamic forces on the cardiac tissues have critical importance, and have a significant role in the proper development of the heart. …”
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Experimental validation of numerical model for thermomechanical performance of material extrusion additive manufacturing process: Effect of infill design & density
Published 2023“…In this study, a thermomechanical numerical model is used to predict the performance of the additive manufacturing (AM) process, i.e., fused filament fabrication (FFF). 3D printing (3DP) process simulations were performed for tensile testing coupons using carbon fiber-reinforced polyamide-6 (PA6-CF) material. The numerical model predicted the effect of infill patterns and densities on the deflections and distortions during the FFF process. …”
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Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002)
Published 2002“…On the other hand, a 3% alcohol consumption (as beer or whisky) maintained for a two months period did not have an effect on fasting plasma TAG concentration while total and LDL cholesterol concentrations showed a significant decrease and HDL cholesterol concentration was moderately increased. …”
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Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats
Published 2015“…A significant increase in serum blood glucose level was observed with hydroxycut intake in the presence of a high-fat diet. …”
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The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis
Published 2018“…Only Cisplatin treatment caused a significant decrease in body weight and increase in serum ALT. …”
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Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
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Wearable Artificial Intelligence for Assessing Physical Activity in High School Children
Published 2022“…There was a pattern of greater PA performance and steps during the weekdays as opposed to the weekend, but these values showed no robust evidence in favor of H1 or statistical significance for step counts. …”