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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
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Clinical Phenotyping and Multimodal Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome From the Middle East and North Africa: Determining Treatment Outcomes and...
Published 2022“…<h3>Objective</h3><p dir="ltr">To evaluate the effectiveness of UPOINT based multimodal treatment on patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), and determine factors that could be associated with clinical improvement.…”
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Mechanisms underlying the effects of caloric restriction on hypertension
Published 2022“…Indeed, CR diminishes phenotypic shift, and suppresses proliferation and migration of VSMCs via pathways involving NO and mTOR. …”
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Correlation of Immunological and Histopathological Features with Gene Expression-Based Classifiers in Colon Cancer Patients
Published 2022“…However, identification of distinct molecular subtypes solely based on histopathology proved to be infeasible. …”
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome
Published 2022“…HER2+/SR−/APO had a significantly lower histological grade than the HER2+/SR−/NST (p < 0.001). …”
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The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects
Published 2022“…This pioneering study provides a reliable estimate of FH prevalence in Qatar based on a significantly large population-based cohort, whilst uncovering the spectrum of genetic variants associated with FH.…”
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Large scale association analysis identifies three susceptibility loci for coronary artery disease
Published 2011“…The parallel study of 88 previously published genes in related phenotypes encompassed 20,225 markers, three quarters of which with imputed genotypes The study was based on our genome-wide genotype data set, with imputation across the whole genome to HapMap II release 22 using HapMap CEU population as a reference. …”
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Immunoprofile of childhood diabetes
Published 2023“…</p> <p>Results: No significant differences between the absolute proportions of Treg and Tcon subsets present was observed in any of the groups studied. …”
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Walking around the preferred speed: examination of metabolic, perceptual, spatiotemporal and stability parameters
Published 2024“…While metabolic, perceptual and spatiotemporal values were sensitive to the smallest change in speed (i.e., 0.5 km·h<sup>−1)</sup>, a significant increase in the rate of carbohydrate oxidation and decrease in % fat oxidation were only observed at speeds above PWS. …”
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Release of colloids in saturated porous media under transient hydro-chemical conditions: A pore-scale study
Published 2021“…Favorable, medium-favorable and unfavorable colloids (i.e., repulsion absent, repulsion at long-range of separation distances and attraction absent with the micromodel surface, respectively) were deposited in the micromodel and then a series of colloid release experiments were conducted at different conditions including increasing the flow rate, decreasing the ionic strength and increasing the solution pH. …”
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Inappropriate Medication Use in Elderly Lebanese Outpatients
Published 2006“…Courses of therapy that were judged inappropriate were further classified according to the specific area of inappropriate use (i.e. Beers’ criteria, duplicate therapy, indication, dose, dose frequency including missing doses, duration and discontinuation of therapy, adverse effects, drug-drug and/or drug-disease interactions, and poor memory). …”
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Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.)
Published 2023“…Spraying of 100 μ M SA at three different Hg levels, i.e., 0 μ M, 50 μ M, 100 μ M, and 150 μ M. The maximum decrease in photosynthetic machinery, plant growth attributes (shoot length, root length, no. of leaves, fresh and dry biomass (shoot and root)), and more accumulation of Hg in leaves, roots, and fruits of sweet pepper. …”
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Cross-sectional proteomic expression in Parkinson's disease-related proteins in drug-naïve patients vs healthy controls with longitudinal clinical follow-up
Published 2023“…Among the DEPs identified, eight proteins—ALCAM, contactin 1, CD36, DUS3, NEGR1, Notch1, TrkB, and BTK— significantly correlated with longitudinal clinical scores including motor and non-motor symptom scores, cognitive function and depression scales, indicating potential predictive values for progression in PD among various phenotypes. …”
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Seroprevalence of camel brucellosis in Qatar
Published 2022“…Camels below breeding age (i.e., < 4 years old) showed decreased seropositivity (3.4%, 95% CI, 0.1–17.8), compared to (22.8%, 95% CI, 17.4–29.0) seropositivity in camels ≥ 4 years of age, with a significant association between age groups and seropositivity (<i>P</i> = 0.02). …”
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Prevalence of Sleep-Disordered Breathing in Prader–Willi Syndrome
Published 2023“…However, REM-AHI was significantly correlated with BMI ( P = 0.031 ). Conclusion. …”
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Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat
Published 2007“…In seven urethane-anesthetized rats, AP and RSNA were recorded under baseline conditions (spontaneous HR = 338 ± 6 beats/min, i.e., 5.6 ± 0.1 Hz) and during 70-s periods of cardiac pacing at 6–9 Hz applied in random order. …”
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Theoretical insight into effect of cation–anion pairs on CO<sub>2</sub> reduction on bismuth electrocatalysts
Published 2020“…The adsorption energy (Eads) and work function (Wf) of the anions increases with decreasing anion size (i.e., Cl<sup>−</sup> > Br<sup>−</sup> > I<sup>−</sup>). …”
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Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…The research found that a significant variation in building height reduces the cooling load more than a gradual height variation, and consequently offers more energy saving. …”
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Response of cauliflower (<i>Brassica oleracea</i> L.) to nitric oxide application under cadmium stress
Published 2022“…The concentration of malondialdehyde (MDA) and Cd accumulation (roots and shoots) increased significantly (P < 0.05) under the increasing levels of Cd in all genotypes of B. oleracea while antioxidant (enzymatic or non-enzymatic) capacity and nutritional status of the plants was decreased with varying levels of Cd in the sand. …”
