Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways by Hadeel, Kheraldine

“…HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer by Kheraldine, Hadeel

“…BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. …”
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome by Faruk Skenderi (6616190)

“…HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity.</p><h2>Other Information</h2> <p> Published in: Breast Cancer Research and Treatment<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10549-022-06578-4" target="_blank">http://dx.doi.org/10.1007/s10549-022-06578-4</a></p>…”

Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv... by Dimassi, Hani

“…The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). …”
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Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer by Rasha M. Sareyeldin (18131371)

“…Despite the anti-HER2 and cytotoxic chemotherapy, HER2 subtype is an aggressive disease with significant mortality. Recent advances in molecular biology techniques, including gene expression profiling, proteomics, and microRNA analysis, have been extensively used to explore the underlying mechanisms behind human breast carcinogenesis and metastasis including HER2-positive breast cancer, paving the way for developing new targeted therapies. …”

Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways by Hadeel Kheraldine (14231609)

“…</p><h3>Conclusion</h3><p dir="ltr">Our findings implicate that a combination of DA and BMS-202 could have a significant impact on the management of HER2-positive breast cancer.…”

Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study by Shubham Chauhan (21334742)

“…</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …”

Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways by Hadeel Kheraldine (14231609)

“…<p>HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”

Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study by Rajesh, Sharma

“…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …”
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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…Bladder cancer accounted for 4.39 million (4.09 to 4.70) DALYs in 2019, and the age-standardised DALY rate decreased significantly by 18.6% (11.2 to 24.3) during the period 1990–2019. …”

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”

Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers by Elias-Rizk, Tamina

“…Background Breast cancer (BC) has been increasing in both prevalence and incidence in Lebanon. …”
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy by Al Bostami, Rouba D.

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Discrimination of breast cancer from benign tumours using Raman spectroscopy by Fiona M. Lyng (2189614)

“…Breast cancer is diagnosed by histopathological examination of breast biopsy material but this is subjective and relies on morphological changes in the tissue. …”

Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer by Ahmed, Amal Elsadig Elamir

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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients by Asmaa Al-mansouri (16931739)

“…<h3>Background</h3><p dir="ltr">The management of chronic kidney disease (CKD) and its complications places a significant burden on patients, resulting in impairment of their health-related quality of life (HR-QOL). …”

Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy by Fiona M. Lyng (2189614)

“…<p dir="ltr">Correction to: Discrimination of breast cancer from benign tumours using Raman spectroscopy. …”

Diagnostic test accuracy of AI-assisted mammography for breast imaging: a narrative review by Daksh Dave (17949239)

“…The motivation for this research lies in addressing the need for enhanced diagnostic tools in breast cancer screening, where early detection can significantly impact patient outcomes. …”

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In conclusion, sumac demonstrated significant oncostatic activities in rodent models of breast carcinoma that were validated by mechanistic studies in vivo and in vitro.…”