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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
Published 2021“…HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer
Published 2025“…BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. …”
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome
Published 2022“…HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity.</p><h2>Other Information</h2> <p> Published in: Breast Cancer Research and Treatment<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10549-022-06578-4" target="_blank">http://dx.doi.org/10.1007/s10549-022-06578-4</a></p>…”
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Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv...
Published 2009“…The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Published 2019“…Despite the anti-HER2 and cytotoxic chemotherapy, HER2 subtype is an aggressive disease with significant mortality. Recent advances in molecular biology techniques, including gene expression profiling, proteomics, and microRNA analysis, have been extensively used to explore the underlying mechanisms behind human breast carcinogenesis and metastasis including HER2-positive breast cancer, paving the way for developing new targeted therapies. …”
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Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways
Published 2024“…</p><h3>Conclusion</h3><p dir="ltr">Our findings implicate that a combination of DA and BMS-202 could have a significant impact on the management of HER2-positive breast cancer.…”
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Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways
Published 2021“…<p>HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers
Published 2024“…Background Breast cancer (BC) has been increasing in both prevalence and incidence in Lebanon. …”
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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Discrimination of breast cancer from benign tumours using Raman spectroscopy
Published 2019“…Breast cancer is diagnosed by histopathological examination of breast biopsy material but this is subjective and relies on morphological changes in the tissue. …”
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Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer
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Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy
Published 2019“…<p dir="ltr">Correction to: Discrimination of breast cancer from benign tumours using Raman spectroscopy. …”
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The effect of foeniculum vulgare seeds on lipidemia, glycemia & liver enzymes. (c2009)
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Diagnostic test accuracy of AI-assisted mammography for breast imaging: a narrative review
Published 2025“…The motivation for this research lies in addressing the need for enhanced diagnostic tools in breast cancer screening, where early detection can significantly impact patient outcomes. …”
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