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Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene
Published 2004“…Several genetic loci have been implicated in the susceptibility to this illness. Evaluated was the role of the CTLA4 exon 1 A49G polymorphism and its role as a risk factor for T1D in our population. …”
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Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv...
Published 2009“…On univariate analysis, both the absolute number of positive lymph nodes and the ALNR were significant predictors of OS. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Evaluation of The Factors Affecting Microplastics and Nanoparticles in Plastic Water Supply Pipes
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The Impact of Adopting Positive Education and Wellbeing Culture on Learners with Special Educational Needs and Disabilities (SEND) in a Private and Mainstream School in Dubai: An E...
Published 2020“…While it has been demonstrated that the role of positive education and wellbeing culture is vital to the optimal development of students within school settings, scrutiny and reluctance to employ novel techniques present a significant challenge and a never-ending list of “to-dos” that hinder the opportunity to ensure an ideal school environment. …”
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Positive Epstein-Barr virus polymerase chain reaction in a case of acute retinal necrosis
Published 2012“…Epstein-Barr virus (EBV) is a ubiquitous DNA virus of the Herpesvirus genus. Its role in the pathogenesis of ocular disease is still controversial. …”
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The Role of Media Literacy in Countering Misinformation
Published 2023“…Results indicate a significant positive association between youth media exposure and them believing in COVID-19 conspiracy theories. …”
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Migration and Net FDI: Role of Governance
Published 2024“…The result revealed that 78% of net FDI comes from migrants and structure governance of hosted countries. Particularly, positive relationship between migration and FDI was significantly stronger at a higher level of governance. …”
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
Published 2019“…For the 3FOOT, there was a non significant decrease in postprandial TG AUC (-2.7%; p = 0.73; 95%CI = -2.0 to 1.5; ES = 0.05) and iAUC (-17.5%; p = 0.41; 95%ci = -2.5 to 1.1; ES = 0.31) from 10 to 34 hrs, respectively. …”
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In vitro results largely confirmed these findings, as neither estrogen nor dihydrotestosterone affected LINE-1 or Alu methylation in Hek293T, HUVEC, or MDA-kb2 cell lines. …”
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The role of institutional quality in reducing environmental degradation in Canada
Published 2024“…Moreover, our findings indicated that there is a statistically significant and positive impact of income on CO<sub>2</sub> emissions, while trade openness exhibits an insignificant impact on CO2 emissions. …”
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The role of protective genetic variants in modulating epigenetic aging
Published 2025“…In conclusion, APOE*E2 protective variants have a positive impact on epigenetic aging, while <i>PCSK9</i> protective variants have a significant effect on DNA methylation signatures. …”
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Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
Published 2025“…The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”
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Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria
Published 2025“…<u>Transmission Electron Microscopy</u> (TEM) analysis verified the significant <u>biocidal</u> activity of Cu-MOFs against both the Gram-negative (<i><u>Escherichia coli</u></i>) and Gram-positive (<u>Staphylococcus aureus</u> and <i>Bacillus subtilis</i>) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu<sup>2+</sup> <u>ion release</u>. …”