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potential non » potential role (Expand Search), potential _ (Expand Search), potential use (Expand Search)
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Enhancing Arabic Reading Proficiency as a Second Language: Unveiling the Significance of Audiobooks for Middle School Students
Published 2024“…Considering audiobooks as a useful tool in improving reading skills and language acquisition, this study aims to explore the potential benefits and effectiveness of using audiobooks as a tool for learning for non-Arab students in Dubai, as there is a diverse student population including individuals from various cultural and linguistic backgrounds which can present significant challenges. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Potential Medical Applications of Chitooligosaccharides
Published 2022“…COS can be produced through enzymatic conversions using chitinases, physical and chemical applications, or a combination of these strategies. COS is of significant interest for pharmacological and medical applications due to its increased water solubility and non-toxicity, with a wide range of bioactivities, including antibacterial, anti-inflammatory, anti-obesity, neuroprotective, anticancer, and antioxidant effects. …”
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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
Published 2023“…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Non-Invasive Biomarkers for Early Lung Cancer Detection
Published 2022“…Therefore, there is an urgent need to identify and validate non-invasive biomarkers for the early diagnosis, prognosis, and treatment of lung cancer for improved patient management. …”
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Modification and Glycation Microalgae Proteins by Non-Thermal Assisted Process
Published 2024“…Additionally, plant proteins are more environmentally sustainable. Therefore, the potential of plant proteins to meet the protein requirements as an alternative source is increasingly gaining importance. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Prescription Pattern of Antidepressants and the Potential for Personalized Medicine in the Qatari Population
Published 2021“…Preponderance of prescription of antidepressants for non-mental health diseases was observed. Population-level prescription trends, as we reported here, when combined with patient genetic variability and outcome data, will have the power to predict the potential for treatment failures and adverse effects of these medications in the population. …”
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Numerical investigation of the potential of using hydrogen as an alternative fuel in an industrial burner
Published 2024“…Mass flow rate (MFR) adjustments and excess air variation significantly influenced emissions, with a 25% MFR increase reducing NOx to 2.8 × 10<sup>-5</sup>, while higher excess air (e.g.,30%) raised NO<sub>x</sub> under lean conditions. …”
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COVID-19 and operating performance: evidence from Shariah-compliant and non-compliant firms
Published 2025“…<h3 dir="ltr">Purpose </h3><p dir="ltr">This study aims to investigate the impact of the COVID-19 pandemic on the operating performance of Shariah-compliant (SC) and non-Shariah-compliant (NSC) firms in the USA, addressing a critical gap in the literature on firm-level operational resilience during unexpected economic shocks. …”
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Screening of Xanthium strumarium (IAPS) Growing on Abandoned Habitats in Khyber Pakhtunkhwa, Pakistan: Perspectives for Phytoremediation
Published 2021“…BAF was found higher in roots than intact plants despite having a significant accumulation of Cd, Pb, and Zn, which shows high metals tolerance of this IAPS. …”