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A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase
Published 2019“…MDS run showed that the C145A mutant demonstrated higher structural deviation, decreased compactness, and the binding patterns. The Y114E mutant showed almost a null effect from the structural analysis. …”
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USING EMBEDDED MACHINE LEARNING IN THE PHYSICAL WORLD TO DETECT TOXICITY IN SPOKEN LANGUAGE
Published 2023“…In our study, quantization demonstrated a significant reduction in model size by almost fourfold and a 3.3-fold decrease in RAM usage. …”
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Adult appendicitis score versus Alvarado score: A comparative study in the diagnosis of acute appendicitis
Published 2023“…The correlation between Alvarado and AAS with HP was significant. AAS ≥ 16 presented sensitivity and specificity of 50 % and 75.47 %, respectively, with PPV of 97.96 % and NPV of 6.02 %, with an accuracy of 51.04 %. …”
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Adrenoceptor Desensitization: Current Understanding of Mechanisms
Published 2024“…On the other hand, long-term desensitization occurs over hours to days and involves receptor downregulation or a decrease in cell surface receptor protein level. …”
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Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.
Published 2019“…MSH2-MSH6 protein complex plays a significant role in maintaining the mismatch repair mechanism. …”
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Platinum degradation mechanisms in proton exchange membrane fuel cell (PEMFC) system: A review
Published 2021“…This review paper summarizes the degradation of platinum catalyst layer that has become a significant issue in the improvement of PEMFCs. The review intends to categorise and provide a clear understanding between disintegration and agglomerate that occurs during platinum degradation. …”
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Impact of time synchronization error on the mode-shape calculation in wireless sensor networks for structural health monitoring
Published 2016“…Numerical results prove that the time synchronization error has a significant impact on the accuracy of the mode shape calculation. …”
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Associations of Recreational and Nonrecreational Physical Activity and Body Weight Change on Cardiovascular Disease Mortality During the Obesogenic Transition in the United States:...
Published 2023“…We found weak (but nonstatistically significant) evidence of mediation effects of body weight change on mortality. …”
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Privacy-Preserving Fog Aggregation of Smart Grid Data Using Dynamic Differentially-Private Data Perturbation
Published 2022“…However, billing accuracy can be degraded by using such additive noise techniques. …”
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Evaluation of nasal septal deviation and maxillary bone and nasal airway dimensions and volumes using cone-beam computed tomography in patients with unilateral palatal canine displ...
Published 2024“…Compared with the control group, PDC subjects had reduced palate thickness and lower nasal airway volume. Two predictors were significant for predicting the odds of PDC occurrence: NSD and maxillary bone volume. …”
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A Framework for Time-Driven Activity-Based Costing for Orthopedic Procedure
Published 2021“…Seven human resources out of eight are significant to model. Accuracy of optimized model is equal to 3%, with RMSE equal to 6. …”
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An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems
Published 2024“…The primary goals of feature selection are to decrease the number of dimensions and enhance classification accuracy in many domains, such as text classification, large-scale data analysis, and pattern recognition. …”
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Integrated planning of spare parts and service engineers with partial backlogging
Published 2017“…In a numerical study, we show that for problems with more than five types of spare parts it is preferable to use approximate evaluations as they become significantly faster than exact evaluation. Moreover, approximation errors decrease as problems get larger. …”
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Knowledge and Perception of and Attitude toward a Premarital Screening Program in Qatar: A Cross-Sectional Study
Published 2022“…Premarital screening (PMS) is a primary preventive measure to decrease the incidence of certain genetic disorders and sexually transmitted diseases. …”
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Computational Analysis for Bioconvection of Microorganisms in Prandtl Nanofluid Darcy-Forchheimer Flow across an Inclined Sheet
Published 2022“…This procedure is widely used for the solution of such problems as it is efficient and cost-effective with a fifth-order accuracy. The significance of immersed parameters on the velocity, temperature, concentration, and bioconvection is shown through figures. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS
Published 2021“…The study revealed that bridging, INR index and being Sudanese are significant predictors of INR normalization. Moreover, CYP2C9 and VKORC1 genetic polymorphisms are influencers to warfarin maintenance weekly dose but none of the genetic factors were associated with the INR decline rate. …”
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