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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Predictors of Arab American adolescent tobacco use
Published 2006“…All trends were significant (p < .001). Logistic regression analyses found ten predictors for ‘smoked a cigarette in past 30 days’ and nine and seven, respectively, for ‘ever smoked a cigarette or narghile’. …”
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Predictors of psychological distress in Lebanese hostages of war
Published 2003“…In the multivariate analysis, the significant predictors for distress were: years of education and increase in religiosity after release. …”
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Prevalence, risk factors, and predictors of pelvic organ prolapse
Published 2012“…Increasing age, increasing vaginal parity, and a body mass index higher than 24 kg/m2 were found to be significant risk factors for POP, with relative risks of 1.09 (P < 0.001), 2.31 (P < 0.0001), and 1.62 (P = 0.048) respectively. …”
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The predictors of successful methotrexate treatment of tubal ectopic pregnancy
Published 2024“…Treatment failure odds were >2 folds higher for each 10-year age increase (<i>p</i>= .017), 32% higher for each 1000 IU/L increase in initial β-hCG level (<i>p</i>= .005), and >2 folds higher in presence of pelvic pain (<i>p</i>= .043).…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq
Published 2015“…ResultsAfter the 2-month intensive phase, physical well-being, functional well-being, and the overall total scores were significantly increased (p<0.01). Furthermore, at completion of TB treatment, there were significant improvements in the overall HRQL as indicated by the FACIT-TB total score and all subscales, except social and economic well-being and spiritual well-being. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Predictors of Pressure Injuries in a Critical Care Unit in Lebanon: Prevalence, Characteristics, and Associated Factors
Published 2018“…Multivariate analysis indicated that length of stay (β= −.110; P = .002), administration of vasopressors (β=−.266; P = .029), and total hours of hypotension (β=−.53; P = .041) were significant predictors of pressure injury. CONCLUSIONS: Vasopressor use, hypotension, and length of stay were associated with an increased likelihood of pressure injury in adults managed in an MSICU. …”
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Predictors of malnutrition among older residents in Qatari long-term care facilities: a retrospective study
Published 2024“…Statistically significant predictors of mortality were malnutrition (OR 24.84, CI 1.09–564) and age (OR 1.07, CI 1.00–1.14).…”
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Predictors, barriers, and facilitators to refugee women’s employment and economic inclusion: A mixed methods systematic review
Published 2024“…Policymakers and researchers worldwide are giving this issue increased attention. This systematic review uses a mixed methods approach and includes 31 studies to explore the predictors, barriers, and facilitators of refugee women’s employment. …”
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Evaluation of psychological distress, burnout and structural empowerment status of healthcare workers during the outbreak of coronavirus disease (COVID-19): a cross-sectional quest...
Published 2024“…The results also revealed that direct work with COVID-19 patients, lower work experience, and high workload during the outbreak of COVID-19 increase the risks of negative psychological consequences.…”
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Increasing consultant-level staffing as a proportion of overall physician coverage improves emergency department length of stay targets
Published 2021“…</p><h3>Conclusions</h3><p dir="ltr">At the study site, in models that adjusted for overall on-duty EP numbers as well as myriad other operational factors, increasing numbers of on-duty Consultants was associated with a statistically and operationally significant reduction in ED LOS.…”
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