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problems based » problem based (Expand Search)
decrease » increase (Expand Search)
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs
Published 2017“…PurposeThere are no published instruments, which measure tutor motivation for conducting small group tutorials in problem-based learning programs. Therefore, we aimed to develop a motivation for tutoring questionnaire in problem-based learning (MTQ-PBL) and evaluate its construct validity. …”
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Examining the perceptions and practices of undergraduate dental students and facilitators about Problem-based Learning (PBL) instructional approach in the United Arab Emirates
Published 2018“…One sample T test for the gender responses were T = - 0.620 and P-value = 0.535 showed no significant difference while One-way ANOVA were T = 4.518 and P-value = 0.001 found significant different between study level in problem-based Learning, ordered, as expected, as follows: Year 5 > Year 4 > Year 3 = Year 2 = Year 1. …”
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A clustering metaheuristic for large orienteering problems
Published 2022“…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …”
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A New Genetic-Based Tabu Search Algorithm For Unit Commitment Problem
Published 2020“…This paper presents a new algorithm based on integrating the use of genetic algorithms and tabu search methods to solve the unit commitment problem. …”
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Psychometric properties of a questionnaire assessing the extent of integration in a problem-based learning curriculum
Published 2025“…At Qatar University and Arabian Gulf University medical colleges, Problem-Based Learning (PBL) is the principal teaching and learning strategy to implement integrated multidisciplinary system-based curriculum. …”
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An Improved Genghis Khan Optimizer based on Enhanced Solution Quality Strategy for Global Optimization and Feature Selection Problems
Published 2024“…Feature selection (FS) is the activity of defining the most contributing feature subset among all used features to improve the superiority of datasets with a large number of dimensions by selecting significant features and eliminating redundant and irrelevant ones. …”
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Sample intelligence-based progressive hedging algorithms for the stochastic capacitated reliable facility location problem
Published 2024“…<p dir="ltr">Selecting facility locations requires significant investment to anticipate and prepare for disruptive events like earthquakes, floods, or labor strikes. …”
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Does problem‐based learning facilitate enactment of learner agency in undergraduate dental curricula? A Q study
Published 2022“…<h3>Introduction</h3><p dir="ltr">Addressing a literature gap on leaner agency in health profession education, this study explores students' perceptions on which aspects of a problem‐based learning (PBL) environment cradle their leaner agency enactment.…”
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Preparing foundation-year students for medical studies in a problem-based learning environment: Students׳ perceptions
Published 2016“…DiscussionStudents reported large improvements among learning skills required in a problem-based medical curriculum, and suggests that students in a premedical foundation year can benefit from a course aiming at preparing students for their future learning in a PBL environment. …”
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The bus sightseeing problem
Published 2023“…<p></p><div> <p>The basic characteristic of vehicle routing problems with profits (VRPP) is that locations to be visited are not predetermined. …”