A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions by Mansour, Hanine

“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... by Katherine R Paulson (8674293)

“…Given the widespread effects of COVID-19, considerable effort will be required to maintain and accelerate progress.</p><p><br></p><h3>Funding</h3><p dir="ltr">Bill & Melinda Gates Foundation.…”

Examining time-to-transport decisions in Emergency Medical Services by Hassan Farhat (9000509)

“…The Schoenfeld plot (Figure 2) demonstrates that multiple variables have a significant impact on increasing the time-to-handover.…”

Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

“…</p><h3>Aim and methods</h3><p dir="ltr">This review aims to study the diagnostic methodology, epidemiology, pathophysiology, and significance of MP management in end-organs, especially the kidneys, cardiovascular system, and outcomes. …”

Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages by Salman M. Toor (8854751)

“…We found high levels of granulocytic myeloid cells (GMCs) in whole blood, but their levels were significantly lower in PBMCs. Importantly, we found significantly higher levels of GMCs in the TME compared to NT. …”

Oral contraceptive pills and possible adverse effects by Stone, Rebecca H

“…Since their introduction to the market, there have been significant changes in the drug content and formulations of these products, in part to decrease the risk of adverse effects. …”
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OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... by Pia Tohme Khalaf (17425551)

“…<p dir="ltr">This study reveals a significant connection between prenatal bonding or attachment during pregnancy and various factors such as maternal age, anxiety, and stress, including those attributed to specific events like the COVID-19 pandemic. …”

DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation by Abdelilah Arredouani (10914455)

“…<p>Failure of the heat shock response is a key event that leads to insulin resistance and type 2 diabetes. …”

Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis by Ayman El-Menyar (440103)

“…PHP did not significantly decrease vasopressor use or late mortality; however, it may reduce the total use of RBCs in the first 24 h. …”

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

Advanced direct air capture of CO₂ using air conditioning systems: a life cycle assessment by Namra Mir (17017734)

“…The integrated system exhibits significantly reduced environmental impacts compared to a standalone DAC unit. …”

Immunoprofile of childhood diabetes by Meritxell Espino-Guarch (15430868)

“…Additionally, all samples were immunoprofiled by multi-parameter flow cytometry to assess the comparative levels of circulating adaptive and innate immune cell types present that potentially contribute to disease progression. </p> <p>Results: No significant differences between the absolute proportions of Treg and Tcon subsets present was observed in any of the groups studied. …”

A component analysis of positive behaviour support plans by Grey, Ian

“…The most commonly implemented components of intervention were setting event changes and quality-of-life-based interventions. …”
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Nasturtium officinalis water extract. (c2009) by Fares, Najwan

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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…Real-world studies of crizanlizumab showed a reduction in complicated VOC events. The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. …”

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study by Obaidullah Zafar (17910572)

“…Hemoglobin levels significantly increased from 6.4 to 11.1 g/dl (<i>p</i> < 0.001) after IV iron treatment, as did ferritin levels, while total iron-binding capacity decreased. …”

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…These interpretive cognitive acts of meaning construction by leaders and followers include significant elements of conceptual thinking and explanation. …”
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Activation of Src kinase in primary colorectal carcinoma An indicator of poor clinical prognosis by Allgayer, Heike

“…In patients who underwent curative resection, a significant correlation with a decreased disease-free survival rate was found (P < 0.0001). …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”