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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The Role of Project Management Soft Skills in Increasing Project Success
Published 2017“…Construction projects are led by project managers who perform the role of a leader of the project and the involved team as a whole. …”
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Effects of Integrated Project Delivery and Information Communication Technology On Project Success
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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OSRA Grant Cycle 1 Public Reports : Project Title: Parenting Style Influences on Child Academic Achievement and University Adjustment
Published 2019“…Employing a year-long research design, the project involved 2267 grade-twelve Omani students in two phases. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Influence of Stakeholder Management on the Successful Implementation of Agile Project Management Methodology in Mega-Events Projects
Published 2019“…The literature revealed of eleven peculiar features of agile in the mega-events context covering the following dimensions; project output & business values, customer involvement, communication and transparency, planning approach, team structure, leadership and culture, organisation structure, governance, learning & coaching, and hybrid method. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Developing a Stochastic Model to Predict Cost Overrun due to the Causes of Projects Delay in Oil Fields Construction Industry
Published 2020“…Therefore, to minimize cost overrun, the study suggest that those involved in a project’s value chain must ensure a smooth execution of project in its early stage so as to limit the high risk associated with the project during in its initial phase. …”
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Organizational factors that influence the success of IT projects
Published 2018“…The reliable differences of sample data have determined that the organizational factors have a significant relationship in measuring project success.…”
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QNL and HERMES Project: Impact Stories
Published 2024“…<p dir="ltr">The presentation highlights the involvement of QNL’s ILDS section in the HERMES project and its significant impact on daily operations, users, and cost savings. …”
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