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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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A Quasi-Oppositional Method for Output Tracking Control by Swarm-Based MPID Controller on AC/HVDC Interconnected Systems With Virtual Inertia Emulation
Published 2021“…<p>This paper presents a comprehensive evaluation of the effect of quasi oppositional - based learning method utilization in output tracking control through a swarm-based multivariable Proportional-Integral-Derivative (SMPID) controller, which is tuned by a novel performance index based on the step response characteristics in multi-input multi-output (MIMO) system. …”
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Effectiveness of a Technology-Based Intervention to Teach Evidence-Based Practice: The EBR Tool
Published 2016“…A statistically significant proportional difference was supported in the RCT nutrition and PharmD intervention groups in participants’ ability to distinguish the credibility of online source materials compared with controls. …”
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Open access of evidence‐based publications
Published 2015“…The purpose of this paper is to assess the proportion and type of open access evidence‐based articles in the form of systematic reviews and meta‐analyses in the field of musculoskeletal disorders and orthopedic surgery. …”
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Modified Elite Opposition-Based Artificial Hummingbird Algorithm for Designing FOPID Controlled Cruise Control System
Published 2023“…This study proposes a novel approach for designing a fractional order proportional-integral-derivative (FOPID) controller that utilizes a modified elite opposition-based artificial hummingbird algorithm (m-AHA) for optimal parameter tuning. …”
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Assessing the Impact of Reactive Power Droop on Inverter Based Microgrid Stability
Published 2021“…Droop control is the most common approach for controlling inverter-based micro-grids. The active power droop gain has always been considered as the main parameter for identifying the micro-grid stability margin. …”
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Feeder protection challenges with high penetration of inverter based distributed generation
Published 2013“…The increasing proportion of inverter based distributed generation (DG) in the power system may limit the short circuit power available at distribution substations and consequently cause significant troubles for the protection of distribution feeders where DG are connected. …”
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A Carbazole-Based Aggregation-Induced Emission “Turn-On” Sensor for Mercury Ions in Aqueous Solution
Published 2025“…In this study, a sensor utilizing aggregation-induced emission (AIE) is introduced as a ’turn-on’ fluorescent sensor specifically designed for mercury ions in aqueous solutions. The sensor, based on carbazole, forms aggregates in aqueous solutions, resulting in a significant 800% enhancement of its fluorescence signal. …”
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