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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Rapid separation of very low concentrations of bacteria from blood
Published 2017“…A rapid and accurate diagnosis of the species and antibiotic resistance of bacteria in septic blood is vital to increase survival rates of patients with bloodstream infections, particularly those with carbapenem-resistant enterobacteriaceae (CRE) infections. …”
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Rapid mercury removal using living indigenous microalgal communities for water treatment applications
Published 2025“…Advanced characterization revealed significant surface modifications, with Scanning Electron Microscopy (SEM) showing increased surface roughness, Fourier Transform Infrared Spectroscopy (FTIR) indicating involvement of hydroxyl, protein, and carbohydrate functional groups, and X-ray Photoelectron Spectroscopy (XPS) confirming Hg(II) binding to oxygen-containing moieties with distinctive Hg 4f peaks at 101.78 and 105.8 eV. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Rapid climate changes and human dynamics during the holocene in the eastern mediterranean (Lower Strymon Valley, northern Greece)
Published 2023“…This sedimentary record represents a significant opportunity for high-resolution palaeoenvironmental studies of the period from 6 to 3 ka cal BP linked to land use and climate change. …”
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Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta...
Published 2023“…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Impacts of twenty years of experimental warming on soil carbon, nitrogen, moisture and soil mites across alpine/subarctic tundra communities
Published 2022“…<p>High-altitude and alpine areas are predicted to experience rapid and substantial increases in future temperature, which may have serious impacts on soil carbon, nutrient and soil fauna. …”
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Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Specifically, we show that vocabulary divergence increases over time, as expected. Due to such significant vocabulary change in Turkish over time, similarity between the periods 1920–1929 and 2010–2019 is 57%. …”
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STARD 13 in prostate cancer. (c2018)
Published 2018“…Knocking down StarD13 by siRNA led to an increase in cell proliferation and adhesion yet a decrease in cell motility and cell speed in prostate cancer. …”
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Formation of Trihalomethanes during Seawater Chlorination
Published 2010“…Chlorination of seawater has shown significant increase in total THMs (TTHMs) and in bromoform concentrations. …”