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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
Published 2025“…However, its reliability is impacted by challenges such as false positives, false negatives, and environmental variability, particularly in low base rate damage scenarios. The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”
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Growth rate and rupture rate of unruptured intracranial aneurysms: a population approach
Published 2009“…We investigate a relationship between growth rate and rupture rate and develop a theoretical model that can predict average behavior of unruptured intracranial aneurysms based on existing clinical data. …”
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of...
Published 2021“…Bladder cancer accounted for 4.39 million (4.09 to 4.70) DALYs in 2019, and the age-standardised DALY rate decreased significantly by 18.6% (11.2 to 24.3) during the period 1990–2019. …”
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A Novel Steganography Technique for Digital Images Using the Least Significant Bit Substitution Method
Published 2022“…Therefore, the proposed work, in this paper, is based on the Least Significant Bit (LSB) substitution method. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Characterization and Modeling of Damage in Steel at Different Strain Rates
Published 2011Get full text
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Safer pedestrian crossing facilities on low-speed roads: Comparison of innovative treatments
Published 2022“…Based on the findings of the study, we conclude that the physical_narrowing treatment outperform other studied treatments since it significantly limits the freedom of drivers to maneuver, forcing them to slow down and give priority to crossing pedestrians.…”
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Rate Adaptation in Dynamic Adaptive Video Streaming Over HTTP
Published 2021Get full text
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Dynamic mechanical characterization and modelling of polypropylene based organoclay nanocomposite
Published 2015“…The experimental characterization was performed by using split Hopkinson pressure bars (SHPB), at different strain rates and temperatures. A significant increase of the yield stress of nanocomposite was shown with the present of organoclay, comparing to neat PP. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008Get full text
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A FeedForward–Convolutional Neural Network to Detect Low-Rate DoS in IoT
Published 2022“…The Canadian Institute of Cybersecurity Denial of Service 2017 (CIC DoS 2017) dataset is used for the study. An iterative wrapper-based feature selection using Support Vector Machine (SVM) is used to derive the significant features required for detection. …”
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A machine learning-based optimization approach for pre-copy live virtual machine migration
Published 2023“…The main difficulty with this approach is the high rate of frequently updating memory pages, referred to as "dirty pages. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
doctoralThesis